Evidence map›Paper›PMID 41676425›Full record

ArticleArchives of medical science : AMS2025

Potential role of microbiota in ovarian cancer treatment.

Monika Englert-Golon, Stefan Sajdak, Katarzyna M Plagens-Rotman, Piotr Merks, Witold Kędzia, Anita Szwed, Magdalena Durda-Masny

Abstract read
In one paragraph

Article in Archives of medical science : AMS, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Monika Englert-GolonDivision of Gynaecological Oncology, Department of Gynaecology, Poznan University of Medical Sciences, Poznan, Poland.
Stefan SajdakPoznan University of Medical Sciences, Poznan, Poland.
Katarzyna M Plagens-RotmanCenter for Pediatric, Adolescent Gynecology and Sexology, Division of Gynecology, Department of Gynecology, Poznan University of Medical Sciences, Poznan, Poland.
Piotr MerksFaculty of Medicine, Collegium Medicum, Cardinal Stefan Wyszyński University, Warsaw, Poland.
Witold KędziaDivision of Gynaecology, Department of Gynaecology, Poznan University of Medical Sciences, Poznan, Poland.
Anita SzwedInstitute of Human Biology and Evolution, Adam Mickiewicz University, Poznan, Poland.
Magdalena Durda-MasnyInstitute of Human Biology and Evolution, Adam Mickiewicz University, Poznan, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, the relationship between microbiota and various aspects of health has become a focal point for scientific investigation. The complex interplay between microbial communities and the development, progression, and treatment of gynaecological malignancies is a burgeoning field not yet fully understood. Recent research indicates that gut, vaginal, and uterine microbiota play a critical role in the response to treatments of ovarian cancer, and particularly in chemotherapy, anti-angiogenic therapy, and PARP inhibitors. Microbiota and microbial metabolites can modulate immune responses, drug metabolism, and angiogenesis, affecting the outcomes of therapy. This review explores the relationship between microbiota and anticancer therapies, and discusses the connection between dysbiosis and treatment resistance, highlighting the potential of microbiota as biomarkers and therapeutic targets in ovarian cancer treatment.

Indexed as

anti-angiogenic therapychemotherapymicrobiotaovarian cancerPARP inhibitors

Identifiers

PMID41676425
PMCPMC12887948

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.