Comprehensive expression of long non-coding RNAs and association with iron and erythropoiesis regulatory proteins in transfusion-dependent β-thalassemia.

Ola M Al-Sanabra, Wafa' J Haza, Abeer A Haza'a, Diya Hasan, Mutaz Jamal Al-Khreisat, Majd M Alsaleh, Ahmad K Al Tibi

Abstract read

In one paragraph

Article in Archives of medical science : AMS, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Endothelial dysfunction and cardiac damage indicators in patients with β-thalassemia major under iron-chelation therapy.Therapeutic advances in hematology · 2026
Article

4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Ola M Al-SanabraDepartment of Medical Laboratory Sciences, Faculty of Allied Medical Sciences, Al-Balqa Applied University, Jordan.

Wafa' J HazaKey Laboratory of Laboratory Medicine, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Zhejiang, China.

Abeer A Haza'aArkan Laboratory, Zarqa, Jordan.

Diya HasanDepartment of Allied Medical Sciences, Zarqa College, Al-Balqa Applied University, Zarqa, Jordan.

Mutaz Jamal Al-KhreisatDepartment of Medical Laboratory Sciences, Faculty of Allied Medical Sciences, Al-Ahliyya Amman University, Amman, Jordan.

Majd M AlsalehDepartment of Allied Medical Sciences, Zarqa College, Al-Balqa Applied University, Zarqa, Jordan.

Ahmad K Al TibiBiolab Diagnostic Laboratories, Amman, Jordan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: β-thalassemia is a genetic disorder characterized by a quantitative defect in β-globin synthesis caused by genetic and epigenetic alterations. However, the expression patterns of Material and methods: Whole blood samples and clinical records were collected from 60 patients with TDβ-T and 20 healthy controls. Expression levels of selected Results: TDβ-T patients exhibited significantly elevated levels of iron and erythropoiesis regulatory proteins, as well as increased expression of Conclusions: This study is the first to demonstrate altered

Indexed as

iron regulatory proteins erythropoiesis regulatory proteinsLncRNA GAS5LncRNA NEAT1transfusion-dependent β-thalassemia

Identifiers

PMID41676412

DOI10.5114/aoms/205790

PMCPMC12887979

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