ReviewAmerican journal of translational research2026
Viral infections in solid organ transplant recipients: immunological principles and intervention strategies.
Review in American journal of translational research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis review aims to examine the challenges of opportunistic viral infections in transplant recipients on long-term immunosuppression and to explore the potential of emerging immunotherapies to improve infection management.
methodsWe summarize the mechanisms and effects of current clinical immunosuppressants, outline the incidence of viral infections following various organ transplants, and discuss the limitations of existing antiviral pharmacotherapies. Furthermore, we systematically review recent advances in novel immunotherapies that harness the patient's immune system.
resultsWhile immunosuppressive regimens significantly improve graft survival, they increase susceptibility to viral infections. Emerging immunotherapies demonstrate promising potential in managing these infections, yet their application in transplant recipients remains underexplored.
conclusionInnovative immunotherapies represent a promising avenue for overcoming the limitations of conventional treatments. Their integration into transplantation practice may enhance long-term outcomes, although further clinical validation is needed.
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