Evidence map›Paper›PMID 41676231›Full record

ArticleACS catalysis2026

Unveiling the Transgalactosylation Switch of a GH42 β‑Galactosidase from the Infant Isolate

Konlarat Phirom-On, Khanh-Trang Vu-Le, Leander Sützl, Benedikt Lehner, David Whelan, Lucile Guerent, Irene Pasini, Marc Schuh, Anita de Ruiter, Markus Blaukopf and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS catalysis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. International journal of systematic and evolutionary microbiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Konlarat Phirom-OnFood Biotechnology Laboratory, Institute of Food Technology, Department of Biotechnology and Food Science, BOKU University, Muthgasse 18, A-1190 Vienna, Austria.
Khanh-Trang Vu-LeFood Biotechnology Laboratory, Institute of Food Technology, Department of Biotechnology and Food Science, BOKU University, Muthgasse 18, A-1190 Vienna, Austria.
Leander SützlFood Biotechnology Laboratory, Institute of Food Technology, Department of Biotechnology and Food Science, BOKU University, Muthgasse 18, A-1190 Vienna, Austria.
Benedikt LehnerFood Biotechnology Laboratory, Institute of Food Technology, Department of Biotechnology and Food Science, BOKU University, Muthgasse 18, A-1190 Vienna, Austria.
David WhelanFood Biotechnology Laboratory, Institute of Food Technology, Department of Biotechnology and Food Science, BOKU University, Muthgasse 18, A-1190 Vienna, Austria.
Lucile GuerentFood Biotechnology Laboratory, Institute of Food Technology, Department of Biotechnology and Food Science, BOKU University, Muthgasse 18, A-1190 Vienna, Austria.
Irene PasiniInstitute of Organic Chemistry, Department of Natural Sciences and Sustainable Resources, BOKU University, Muthgasse 18, A-1190 Vienna, Austria.
Marc SchuhDoctoral Programme BioToP-Biomolecular Technology of Proteins, BOKU University, Muthgasse 18, A-1190 Vienna, Austria.
Anita de RuiterInstitute for Molecular Modeling and Simulation, Department of Natural Sciences and Sustainable Resources, BOKU University, Muthgasse 18, A-1190 Vienna, Austria.
Markus BlaukopfInstitute of Organic Chemistry, Department of Natural Sciences and Sustainable Resources, BOKU University, Muthgasse 18, A-1190 Vienna, Austria.
Dietmar HaltrichFood Biotechnology Laboratory, Institute of Food Technology, Department of Biotechnology and Food Science, BOKU University, Muthgasse 18, A-1190 Vienna, Austria.ORCID https://orcid.org/0000-0002-8722-8176
Chris OostenbrinkDoctoral Programme BioToP-Biomolecular Technology of Proteins, BOKU University, Muthgasse 18, A-1190 Vienna, Austria.ORCID https://orcid.org/0000-0002-4232-2556
Thu-Ha NguyenFood Biotechnology Laboratory, Institute of Food Technology, Department of Biotechnology and Food Science, BOKU University, Muthgasse 18, A-1190 Vienna, Austria.ORCID https://orcid.org/0000-0002-5253-6865

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

β-Galactosidases catalyze the transgalactosylation of lactose to produce prebiotic galacto-oligosaccharides (GOS), key fortificants in infant formulas. A β-galactosidase from the infant isolate

Indexed as

galacto-oligosaccharides (GOS)glycoside hydrolase (GH) family 42protein engineeringtransgalactosylationwater tunnelβ-galactosidase

Identifiers

PMID41676231
PMCPMC12887932

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.