ArticleDEN open2026
Transient Global Amnesia After Screening Esophagogastroduodenoscopy: Incidence and Risk Factors in a 20-Year Single-Center Cohort.
Article in DEN open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aim: Transient global amnesia (TGA) after esophagogastroduodenoscopy (EGD) has been described only in case reports. Because sudden-onset amnesia can mimic stroke and other acute central nervous system disorders, TGA requires careful differentiation in the acute setting, and clinicians need to be familiar with this condition. We estimated its incidence after screening EGD and identified associated risk factors in a large single-center cohort. Methods: We retrospectively reviewed 420,979 screening EGDs at a single health checkup center (April 2005-March 2025). All EGDs were performed without sedation, using topical pharyngeal anesthesia only. TGA cases were ascertained from the endoscopy adverse-event registry and confirmed. For analyses, three non-TGA controls per TGA case (1:3 ratio) were randomly selected from examinees undergoing EGD on the same calendar date, using same-day matching. Odds ratios (ORs) were estimated using conditional logistic regression. Results: TGA occurred in 64 episodes in 63 individuals of 420,979 examinations (0.0152%). In route-specific analyses from April 2008, the transoral route carried a higher risk than the transnasal route (Fisher's exact test Conclusions: The incidence of post-EGD TGA was very low at 15.2 per 100,000 examinations (0.0152%). Older age, female sex, transoral insertion, and treated dyslipidemia were independently associated with post-EGD TGA. A transnasal approach might be a potential risk-reduction strategy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.