Evidence map›Paper›PMID 41675929›Full record

ArticleFrontiers in cellular and infection microbiology2025

Single-cell RNA-sequencing of peripheral blood mononuclear cells reveals the transcriptome profile of

Nouhoum Dibo, Zhijun Zhou, Xianshu Liu, Zhuolin Li, Shukun Zhong, Jiajing Zhang, Huilan Wang, Bo Li, Xiaohui Yang, Yuehui Li and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Nouhoum DiboDepartment of Medical Parasitology, Xiangya School of Basic Medical Sciences, Central South University, Changsha, Hunan, China.
Zhijun ZhouDepartment of Laboratory Animals, Hunan Key Laboratory of Animal Models for Human Diseases, Central South University, Changsha, Hunan, China.
Xianshu LiuDepartment of Medical Parasitology, Xiangya School of Basic Medical Sciences, Central South University, Changsha, Hunan, China.
Zhuolin LiDepartment of Medical Parasitology, Xiangya School of Basic Medical Sciences, Central South University, Changsha, Hunan, China.
Shukun ZhongDepartment of Medical Parasitology, Xiangya School of Basic Medical Sciences, Central South University, Changsha, Hunan, China.
Jiajing ZhangDepartment of Medical Parasitology, Xiangya School of Basic Medical Sciences, Central South University, Changsha, Hunan, China.
Huilan WangHunan Key Laboratory of Immunology and Transmission Control of Schistosomiasis, Yueyang, Hunan, China.
Bo LiHunan Key Laboratory of Immunology and Transmission Control of Schistosomiasis, Yueyang, Hunan, China.
Xiaohui YangNursing Department, The Third Xiangya Hospital of Central South University, Changsha, Hunan, China.
Yuehui LiDepartment of Biomedical Information, School of Life Sciences, Central South University, Changsha, Hunan, China.
Xiang WuDepartment of Medical Parasitology, Xiangya School of Basic Medical Sciences, Central South University, Changsha, Hunan, China.
Shuaiqin HuangDepartment of Medical Parasitology, Xiangya School of Basic Medical Sciences, Central South University, Changsha, Hunan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The reed vole, Methods: We performed single-cell RNA-seq to investigate the peripheral blood mononuclear cells (PBMCs) responses to Results: The major cell types identified in the PBMCs of the two species were monocytes, dendritic cells (DCs), T cells, NK cells, B cells, and erythrocytes. We observed that the population of monocytes decreased considerably in the bloodstream after infection in both Discussion: Together, our results suggest that both the innate and adaptive immune responses were activated in the peripheral blood of

Indexed as

ArvicolinaeLeukocytes, MononuclearSchistosoma japonicumSchistosomiasis japonicaTranscriptomeAnimalsDendritic CellsFemaleGene Expression ProfilingMiceSingle-Cell AnalysisSingle-Cell Gene Expression AnalysisMicrotus fortisnatural resistanceperipheral blood mononuclear cellssingle-cell RNA sequencingS. japonicum

Identifiers

PMID41675929
PMCPMC12886473

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.