Evidence map›Paper›PMID 41675731›Full record

ArticleAnnals of medicine and surgery (2012)2026

Microbial metabolites from gut bacteria as novel anti-cancer agents.

Muhammad Shahid Mehmood, Inbsaat Iqbal, Fatima Hajj

Abstract readLetter
In one paragraph

Article in Annals of medicine and surgery (2012), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Muhammad Shahid MehmoodInstitute of Microbiology, University of Agriculture Faisalabad, Faisalabad, Pakistan.
Inbsaat IqbalDepartment of Radiotherapy and Medical Oncology, King Edward Medical University, Lahore, Pakistan.
Fatima HajjFaculty of Medical Sciences, Lebanese University, Beirut, Lebanon.ORCID https://orcid.org/0009-0005-5542-4497

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent evidence highlights the potential of gut microbial metabolites as promising anticancer agents, with mechanisms distinct from those of conventional chemotherapeutics. Short-chain fatty acids, particularly butyrate, exhibit histone deacetylase inhibitory activity, leading to apoptosis and cell-cycle arrest in colorectal and breast cancers. Reuterin, a redox-active metabolite of

Indexed as

bacteriocinsbile acidsbutyratecancer therapygut microbiotaimmunomodulationinosinemicrobial metabolitesnovel anticancer agentsreuterin

Identifiers

PMID41675731
PMCPMC12889397

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.