Evidence map›Paper›PMID 41675688›Full record

ArticleMolecular therapy. Oncology2026

Identification and evaluation of novel intergenic sites in the vaccinia virus genome for transgene insertion.

Carmen Bueno-Merino, Ana Del Canizo, Miquel Conesa, Maria Barcia, Ignacio Sallent, Joan Manils, Sonia-Vanina Forcales, Concepció Soler, Juan J Rojas

Abstract read
In one paragraph

Article in Molecular therapy. Oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Carmen Bueno-MerinoImmunology Unit, Department of Pathology and Experimental Therapies, School of Medicine, University of Barcelona - UB, 08907 L'Hospitalet de Llobregat, Spain.
Ana Del CanizoImmunology Unit, Department of Pathology and Experimental Therapies, School of Medicine, University of Barcelona - UB, 08907 L'Hospitalet de Llobregat, Spain.
Miquel ConesaImmunology Unit, Department of Pathology and Experimental Therapies, School of Medicine, University of Barcelona - UB, 08907 L'Hospitalet de Llobregat, Spain.
Maria BarciaImmunology Unit, Department of Pathology and Experimental Therapies, School of Medicine, University of Barcelona - UB, 08907 L'Hospitalet de Llobregat, Spain.
Ignacio SallentImmunology Unit, Department of Pathology and Experimental Therapies, School of Medicine, University of Barcelona - UB, 08907 L'Hospitalet de Llobregat, Spain.
Joan ManilsImmunology Unit, Department of Pathology and Experimental Therapies, School of Medicine, University of Barcelona - UB, 08907 L'Hospitalet de Llobregat, Spain.
Sonia-Vanina ForcalesImmunology Unit, Department of Pathology and Experimental Therapies, School of Medicine, University of Barcelona - UB, 08907 L'Hospitalet de Llobregat, Spain.
Concepció SolerImmunology Unit, Department of Pathology and Experimental Therapies, School of Medicine, University of Barcelona - UB, 08907 L'Hospitalet de Llobregat, Spain.
Juan J RojasImmunology Unit, Department of Pathology and Experimental Therapies, School of Medicine, University of Barcelona - UB, 08907 L'Hospitalet de Llobregat, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vaccinia virus (VACV) is widely used as a vaccine and oncolytic vector due to its safety profile and its capacity to accommodate exogenous DNA. However, its compact genome offers limited

Indexed as

insertion siteintergenicMT: Regular Issueoncolytictransgenevaccinia virus

Identifiers

PMID41675688
PMCPMC12887270

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.