Impact of in-hospital body mass index variation on 28-day mortality in critically ill surgical patients: a multi-center retrospective analysis.

Bocheng Yang, Gang Xu, Jiagui Zhao, Xiaoan Yang, Qinghe Huang

Abstract read

In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Early Body Mass Index Trajectory as a Marker of Metabolic and Nutritional Changes in Critically Ill Patients.Nutrients · 2026
Article

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bocheng Yang *Division of Plastic Surgery, Zhongshan Hospital Xiamen University, School of Medicine, Xiamen University, Xiamen, China.

Gang Xu *Medical Emergency Center of Xiamen, Xiamen, China.

Jiagui Zhao *Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu, China.

Xiaoan YangDepartment of Infectious Diseases, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.

Qinghe HuangDepartment of ICU, Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The prognostic value of dynamic body mass index (BMI) changes during hospitalization in surgical intensive care unit (ICU) patients admitted emergently remains unclear. This study aimed to investigate the association between in-hospital BMI change and 28-day mortality in this high-risk population. Methods: This retrospective cohort study utilized data from the eICU Collaborative Research Database (2014-2015). A total of 20,543 adult surgical ICU patients admitted via the emergency department (ED) were included. BMI change was calculated as discharge BMI minus admission BMI. Multivariable Cox regression, restricted cubic splines, and subgroup analyses were employed to evaluate the association between BMI change and mortality. Results: The 28-day ICU mortality was 4.70%. BMI change exhibited a U-shaped, non-linear association with death: risk declined modestly as BMI rose toward the nadir of -1.75 kg/m Conclusion: In-hospital BMI change is a significant predictor of 28-day mortality in surgical ICU patients admitted via the ED. A moderate reduction in BMI (-1.75 kg/m

Indexed as

28-day mortalityBMI changeemergency department admissionsurgical ICUU-shaped relationship

Identifiers

PMID41675631

DOI10.3389/fmed.2025.1738654

PMCPMC12886406

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