Evidence map›Paper›PMID 41675526›Full record

ArticleCanadian journal of kidney health and disease2026

Canadian Society of Nephrology Commentary on the Evolving Kidney Disease Improving Global Outcomes Adult Glomerulonephritis Guidelines.

Arenn Jauhal, Reem Mustafa, Anna Mathew, Louis Girard, Sean Barbour, Bhanu Prasad, Lavanya Bathini, Penelope Poyah, Stephan Troyanov, Ratna Samanta and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Canadian journal of kidney health and disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Arenn JauhalDivision of Nephrology, Department of Medicine, University Health Network, Temerty Faculty of Medicine, University of Toronto, ON, Canada.ORCID https://orcid.org/0000-0001-5246-8324
Reem MustafaDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada.
Anna MathewDivision of Nephrology, Department of Medicine, McMaster University, Hamilton, ON, Canada.
Louis GirardDivision of Nephrology, Department of Medicine, Cumming School of Medicine, University of Calgary, AB, Canada.
Sean BarbourDivision of Nephrology, Department of Medicine, University of British Columbia, Vancouver, Canada.
Bhanu PrasadDivision of Nephrology, Department of Medicine, Regina General Hospital, SK, Canada.ORCID https://orcid.org/0000-0002-1139-4821
Lavanya BathiniDivision of Nephrology, Department of Medicine, University of Alberta Hospital, University of Alberta, Edmonton, Canada.
Penelope PoyahDivision of Nephrology, Department of Medicine, Nova Scotia Health Renal Program, Faculty of Medicine, Dalhousie University, Halifax, Canada.ORCID https://orcid.org/0000-0002-7575-2835
Stephan TroyanovDivision of Nephrology, Department of Medicine, Hôpital du Sacré-Cœur-de-Montréal, University of Montreal, QC, Canada.
Ratna SamantaDivisions of Nephrology and Experimental Medicine, Department of Medicine, McGill University Health Centre, Montreal, QC, Canada.ORCID https://orcid.org/0000-0002-3014-7316
Jocelyn GarlandDivision of Nephrology, Department of Medicine, Kingston General Hospital, Queen's University, ON, Canada.
Todd FairheadDivision of Nephrology, Department of Medicine, The Ottawa Hospital, Faculty of Medicine, University of Ottawa, ON, Canada.
Michael WalshDivision of Nephrology, Department of Medicine, McMaster University, Hamilton, ON, Canada.ORCID https://orcid.org/0000-0001-8292-2014
Heather ReichDivision of Nephrology, Department of Medicine, University Health Network, Temerty Faculty of Medicine, University of Toronto, ON, Canada.ORCID https://orcid.org/0000-0001-8951-5518
Shih-Han HuangDivision of Nephrology, Department of Medicine, London Health Sciences Centre, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
Jenny NgDivision of Nephrology, Clinical Pharmacist, Sunnybrook Health Sciences Centre, Toronto, ON, Canada.
Judith MarinSt. Paul's Hospital, Pharmaceutical Sciences, University of British Columbia, Vancouver, Canada.ORCID https://orcid.org/0000-0001-9317-8809
Michelle HladunewichDivision of Nephrology, Department of Medicine, Sunnybrook Health Sciences Centre, Temerty School of Medicine, University of Toronto, ON, Canada.ORCID https://orcid.org/0000-0001-9227-4292

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose of review: The purpose of this commentary is to address the challenges of implementing the evolving Kidney Disease Improving Global Outcomes (KDIGO) glomerulonephritis (GN) guidelines within the Canadian health care context, highlighting barriers to adoption of the guidelines and discussing contextual issues unique to Canada. Sources of information: The KDIGO 2021 guidelines with 2024 updates in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis and lupus nephritis, as well as the 2025 updated guideline for immunoglobulin A (IgA) nephropathy. Methods: A Canadian Society of Nephrology (CSN) working group with expertise in GN was formed, representing nephrologists, pathologists, pharmacists, and patient partners with geographic representation from across Canada. Recommendations and practice points were reviewed by member surveys, with discussions to reach consensus and frame the commentary. Key findings: The commentary highlights diagnostic investigations, the role of immune treatments for primary glomerular diseases, and the growing role of conservative kidney therapies. Limitations: A review of the quality of evidence was not undertaken. Implementation and uptake of the guidelines will vary across each province given drug availability and cost. Implications: The commentary aims to provide tailored guidance to enhance the care of Canadians living with glomerular disease.

Indexed as

Canadian Society of Nephrologyclinical guidelinesglomerulonephritisKDIGO

Identifiers

PMID41675526
PMCPMC12886736

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.