Evidence map›Paper›PMID 41675375›Full record

ArticleQuantitative biology (Beijing, China)2025

Quantifying cell fate change under different stochastic gene activation frameworks.

Xinxin Chen, Ying Sheng, Liang Chen, Moxun Tang, Feng Jiao

Abstract read
In one paragraph

Article in Quantitative biology (Beijing, China), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xinxin ChenGuangzhou Center for Applied Mathematics Guangzhou University Guangzhou China.
Ying ShengGuangzhou Center for Applied Mathematics Guangzhou University Guangzhou China.
Liang ChenGuangzhou Center for Applied Mathematics Guangzhou University Guangzhou China.
Moxun TangDepartment of Mathematics Michigan State University East Lansing Michigan USA.
Feng JiaoGuangzhou Center for Applied Mathematics Guangzhou University Guangzhou China.ORCID https://orcid.org/0000-0002-5894-8094

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gene transcription is a stochastic process characterized by fluctuations in mRNA levels of the same gene in isogenic cell populations. A central question in single-cell studies is how to map transcriptional variability to phenotypic differences between isogenic cells. We introduced a measurable and statistical transcription threshold

Indexed as

cell fate changemRNA distributionstatistical transcription thresholdstochastic gene transcriptiontranscription noise

Identifiers

PMID41675375
PMCPMC12806088

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.