ReviewTranslational gastroenterology and hepatology2026
Integrated care management model for liver transplantation: a narrative review and single-center implementation experience.
Review in Translational gastroenterology and hepatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
11 authors.
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Abstract
Background and Objective: Liver transplantation (LT) is the most effective end-stage liver disease (ESLD) therapeutic intervention. However, in China, many liver transplant recipients lack a comprehensive management approach. This narrative review summarizes the current deficiencies in long-term post-transplant care and proposes a comprehensive model for Integrated Care Management (ICM) aimed at improving long-term outcomes after LT. Methods: An extensive electronic literature search was performed using PubMed database to identify relevant articles. The search included prospective clinical trials, observational trials, case-control studies, systematic reviews with or without meta-analysis. Articles were limited to English and Chinese language publications. The following Medical Subject Headings (MeSH) terms and free-text keywords were combined with Boolean operators: ("liver transplantation" OR "liver transplant*" OR "orthotopic liver transplantation" OR "OLT") AND ("postoperative management" OR "whole-course management" OR "perioperative care" OR "long-term follow-up") AND ("immunosuppress*" OR "tacrolimus" OR "cyclosporine" OR "mycophenolate" OR "infection prophylaxis" OR "graft function" OR "rejection" OR "biliary stricture" OR "hepatic artery thrombosis" OR "renal dysfunction" OR "hepatitis B recurrence" OR "hepatitis C recurrence"). Key Content and Findings: Research has shown the global number of LT recipients continues to rise, affecting millions of individuals and placing a substantial burden on healthcare systems worldwide. Despite considerable progress over the past three decades in surgical techniques, perioperative care, and immunosuppressive therapy, long-term post-transplant management has received comparatively limited attention from both the public and policy-makers. This neglect has contributed to suboptimal long-term outcomes, including increased mortality and reduced quality of life among recipients. Conclusions: A comprehensive model for ICM may be a new direction to improve the long-term outcomes after LT in the future.
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