ArticleTranslational gastroenterology and hepatology2026
Video capsule endoscopy in very early onset inflammatory bowel disease: a multicenter retrospective study from the Chinese Pediatric VCE Study Group.
Article in Translational gastroenterology and hepatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Video capsule endoscopy (VCE) is a noninvasive modality in the assessment among patients with very early onset inflammatory bowel disease (VEOIBD). Little is known about the application of VCE in this rare disorder. The aim of this study is to evaluate the features of patients with VEOIBD undergoing VCE. Methods: We retrospectively reviewed 37 VEOIBD patients who underwent VCE from five tertiary centers. Clinical data, including endoscopic findings and treatment were retrieved from medical records. Next generation sequencing was performed to confirm the monogenic defects. Results: During a decade, a total of 37 VEOIBD patients were retrospectively included from 5 specialist centers. The total number of VCE procedures performed was 58. The VCE was performed at an average age of 7.8±3.2 years. Twelve patients had undergone follow-up VCE. Next-generation sequencing confirmed the known monogenic inflammatory bowel disease (IBD) in 18 patients. Multiple ulcers, erosions and pseudo-polyps have been identified among patients with Conclusions: This multicenter study showed the features of small bowel lesions among VEOIBD by VCE. Safety of VCE in VEOIBD patients have also been demonstrated.
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