Evidence map›Paper›PMID 41675266›Full record

ArticleTurk gogus kalp damar cerrahisi dergisi2026

Incidence and clinical implications of aortic root thrombosis in LVAD patients: A single-center experience.

Mehmet Karahan, Sinan Sabit Kocabeyoğlu, Doğan Emre Sert, Omaç Tüfekçioğlu, Burcu Demirkan, Hülya Özen, Ümit Kervan, Mehmet Ali Özatık

Abstract read
In one paragraph

Article in Turk gogus kalp damar cerrahisi dergisi, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mehmet KarahanClinic of Cardiovascular Surgery, Ankara Bilkent City Hospital, Ankara, Türkiye.ORCID 0000-0003-1705-4999
Sinan Sabit KocabeyoğluClinic of Cardiovascular Surgery, Ankara Bilkent City Hospital, Ankara, Türkiye.ORCID 0000-0001-5492-4004
Doğan Emre SertClinic of Cardiovascular Surgery, Ankara Bilkent City Hospital, Ankara, Türkiye.ORCID 0000-0003-1053-114X
Omaç TüfekçioğluClinic of Cardiology, Ankara Bilkent City Hospital, Ankara, Türkiye.ORCID 0000-0003-3478-9292
Burcu DemirkanClinic of Cardiology, Ankara Bilkent City Hospital, Ankara, Türkiye.ORCID 0000-0001-5261-4299
Hülya ÖzenDepartment of Medical Informatics, University of Health Sciences Türkiye Gülhane Faculty of Medicine, Ankara, Türkiye.ORCID 0000-0003-4144-3732
Ümit KervanClinic of Cardiovascular Surgery, Ankara Bilkent City Hospital, Ankara, Türkiye.ORCID 0000-0001-7198-069X
Mehmet Ali ÖzatıkClinic of Cardiovascular Surgery, Ankara Bilkent City Hospital, Ankara, Türkiye.ORCID 0000-0002-0479-7518

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Aortic root thrombosis (ART) in left ventricular assist device (LVAD) patients has gained attention due to potential clinical consequences. This study aims to assess the clinical outcomes associated with ART in LVAD patients. Methods: We retrospectively evaluated adult patients who received LVAD implants at our center between January 2020 and March 2022. Pre-operative data, including demographics, laboratory values, and echocardiographic assessments, were similar between the ART and non-ART groups. Composite outcomes such as cerebrovascular events, pump thrombosis, myocardial infarction, embolic events, bleeding, right ventricular (RV) failure, and mortality post-discharge were examined. Results: The study included 44 outpatients (36 HeartMate 3, 8 HeartWare). ART was identified in 20 patients (45%) post-discharge. The "no ART" group had a mean age of 47±10 years (23 of 24 patients were male, 95.8%), while the "ART" group had a mean age of 48±12 years (15 of 20 patients were male, 75%), with no significant age difference (p>0.05). Thrombosis occurred at a median of 59 days post-implantation, primarily affecting the non-coronary cusp in 50% of the ART group. The median follow-up period was 416 days. No significant differences were found in composite outcomes (p=0.276), mortality (p=0.814), bleeding (p=0.808), or RV failure (p=0.197). Conclusion: ART may be under-recognized in LVAD patients, potentially leading to cardiac and end-organ damage. While ART does not significantly impact mortality, it emphasizes the need for careful management of LVAD patients.

Indexed as

Aortic root thrombosisheart failureLVAD

Identifiers

PMID41675266
PMCPMC13051742

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.