ArticleHealth science reports2026
Environmental, Nutritional, and Therapeutic Factors That Affect Surgical Wound Healing: A Narrative Review of Experimental Findings From the Last 5 Years.
Article in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aims: Wound healing is a crucial aspect of clinical outcomes following surgical procedures. Various physiological, environmental, and lifestyle factors impact healing time and quality. Methods: This review is based on the latest experimental findings pertaining to surgical wound management and healing, based on a PubMed search of experiments from the last 5 years. Topics of interest were infection control, nutrition, radiation-induced skin injury (RSI), and closed-incisional negative pressure wound therapy (CiNPWT). The study mainly assesses wound healing by primary intention and focuses on easily implemented therapies. Results: 403 articles were screened regarding infection prevention with 336 excluded based on title and preview of content. 67 abstracts were further reviewed which yielded 32 articles for analysis. Overall, povidone-iodine is shown to improve the rate of wound healing and helps minimize complications such as infections or wound dehiscence while creating a sterile field due to its antimicrobial properties. It remains a standard of comparison for other anti-infectives. Nutritional factors such as veganism may impair surgical wound healing, whereas maintaining appropriate albumin levels may be protective. Employment of nutritional screenings may improve overall outcomes post-operatively, and oral probiotics improve soft tissue healing after incision, in at least one study. Pycnogenol® and Centellicum® may have applications to improve surgical site healing, since supplementation demonstrates improved perfusion and other favorable metrics. Management of RSI is a field of much exploration, with many topicals shown effective. Recently, hydrogels and even injection of stromal vascular factor show promising results. CiNPWT is found to improve overall surgical outcomes in diverse wounds, and sponge width is an important consideration. Conclusion: Consideration of the findings discussed, along with their potential combinations and applications, may serve to improve surgical wound healing.
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Registered trials
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