Evidence map›Paper›PMID 41675199›Full record

ArticleJournal of human immunity2026

Viral infection and brain inflammation with seizures in PARK7 deficiency.

Jonas Lønskov, Annika Sünderhauf, Sisse Andersen, Caroline Bækmann Jeppesen, Franziska Winzig, Daniëla Maria Hinke, Johanna L Heinz, Kenneth Thomsen, Mette B Thorup, Thomas Zillinger and 9 more

Abstract read
In one paragraph

Article in Journal of human immunity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Jonas Lønskov *Department of Biomedicine, Aarhus University, Aarhus, Denmark.ORCID https://orcid.org/0009-0009-5050-1384
Annika Sünderhauf *Department of Biomedicine, Aarhus University, Aarhus, Denmark.ORCID https://orcid.org/0000-0003-0591-8809
Sisse Andersen *Department of Biomedicine, Aarhus University, Aarhus, Denmark.ORCID https://orcid.org/0009-0006-6090-1996
Caroline Bækmann JeppesenDepartment of Clinical Medicine, Aarhus University, Aarhus, Denmark.ORCID https://orcid.org/0000-0002-6502-4586
Franziska WinzigDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.ORCID https://orcid.org/0009-0005-7186-7319
Daniëla Maria HinkeDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.ORCID https://orcid.org/0000-0002-3932-8762
Johanna L HeinzDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.ORCID https://orcid.org/0000-0002-9093-0011
Kenneth ThomsenDepartment of Dermatology and Venereology, Aarhus University Hospital, Aarhus, Denmark.ORCID https://orcid.org/0000-0002-2337-7746
Mette B ThorupDepartment of Radiology, Aarhus University Hospital, Aarhus, Denmark.ORCID https://orcid.org/0009-0005-4478-397X
Thomas ZillingerDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.ORCID https://orcid.org/0000-0002-0866-4835
Bettina BundgaardDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.ORCID https://orcid.org/0009-0004-6979-4256
Kerstin De KeukeleereDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.ORCID https://orcid.org/0000-0001-8924-3997
Sofie Eg JørgensenDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.ORCID https://orcid.org/0000-0002-2700-0882
Jakob EkDepartment of Clinical Genetics, Rigshospitalet, Copenhagen, Denmark.ORCID https://orcid.org/0009-0004-8492-029X
Elsebet ØstergaardDepartment of Clinical Genetics, Rigshospitalet, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-8047-063X
Jakob ChristensenDepartment of Clinical Medicine, Aarhus University, Aarhus, Denmark.ORCID https://orcid.org/0000-0002-9385-6435
Mette Møller HandrupDepartment of Clinical Medicine, Aarhus University, Aarhus, Denmark.ORCID https://orcid.org/0000-0001-5341-239X
Renee M van der Sluis *Department of Biomedicine, Aarhus University, Aarhus, Denmark.ORCID https://orcid.org/0000-0002-7668-2517
Trine H Mogensen *Department of Biomedicine, Aarhus University, Aarhus, Denmark.ORCID https://orcid.org/0000-0002-1853-9704

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Respiratory syncytial virus (RSV) is a major health problem worldwide, particularly in infants and young children. The infection can progress to life-threatening lower respiratory disease and, in rare cases, involves the central nervous system. We explore the pathophysiology in a child with high fever, seizures, and encephalopathy with brain inflammation during severe RSV infection. Whole-genome sequencing revealed homozygosity for a rare loss-of-function variant in the early-onset Parkinson-related gene

Identifiers

PMID41675199
PMCPMC12889338

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.