Evidence map›Paper›PMID 41675164›Full record

ArticleiMetaOmics2025

Selective expansion of gut antibiotic resistome and underlying pathways involved in type 1 diabetes.

Guozhu Ye, Yifang Duan, Haining Huang, Guoyou Chen, Minghui Li, Ricardo David Avellán-Llaguno, Qiansheng Huang

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in iMetaOmics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Guozhu YeXiamen Key Laboratory of Indoor Air and Health, Center for Excellence in Regional Atmospheric Environment, Key Lab of Urban Environment and Health, Institute of Urban Environment Chinese Academy of Sciences Xiamen China.ORCID 0000-0001-5173-2293
Yifang DuanXiamen Key Laboratory of Indoor Air and Health, Center for Excellence in Regional Atmospheric Environment, Key Lab of Urban Environment and Health, Institute of Urban Environment Chinese Academy of Sciences Xiamen China.
Haining HuangXiamen Key Laboratory of Indoor Air and Health, Center for Excellence in Regional Atmospheric Environment, Key Lab of Urban Environment and Health, Institute of Urban Environment Chinese Academy of Sciences Xiamen China.
Guoyou ChenCollege of Pharmacy, Daqing Campus Harbin Medical University Daqing China.
Minghui LiCollege of Pharmacy, Daqing Campus Harbin Medical University Daqing China.
Ricardo David Avellán-LlagunoXiamen Key Laboratory of Indoor Air and Health, Center for Excellence in Regional Atmospheric Environment, Key Lab of Urban Environment and Health, Institute of Urban Environment Chinese Academy of Sciences Xiamen China.
Qiansheng HuangXiamen Key Laboratory of Indoor Air and Health, Center for Excellence in Regional Atmospheric Environment, Key Lab of Urban Environment and Health, Institute of Urban Environment Chinese Academy of Sciences Xiamen China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Selective expansion of gut antibiotic resistance genes (including glycopeptides, tetracyclines, macrolide-lincosamide-streptogramins, and beta-lactams) was observed in type 1 diabetic rats. Interestingly, a similar expansion of gut antibiotic resistome occurred in diabetic patients. Selective expansion of gut antibiotic resistome was correlated with hyperglycemia and gut microbial community (particularly order

Identifiers

PMID41675164
PMCPMC12806347

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.