Evidence map›Paper›PMID 41675154›Full record

ArticleiMetaOmics2025

A human skin microbiome reference catalog and the skin microbial landscape of plateau adults.

Yi Liu, Zhiming Li, Chao Zhang, Bo Li, Weiwei Jiang, Hang Li, Lei Zhang, Hefu Zhen, Shujun Bao, Xiong Li and 20 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iMetaOmics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Yi LiuDepartment of Dermatology, Shanghai Key Laboratory of Molecular Medical Mycology, Shanghai Changzheng Hospital Naval Medical University Shanghai China.
Zhiming LiBGI Research Shenzhen China.ORCID 0000-0001-5589-1136
Chao ZhangDepartment of Dermatology, Shanghai Key Laboratory of Molecular Medical Mycology, Shanghai Changzheng Hospital Naval Medical University Shanghai China.
Bo LiThe General Hospital of PLA Tibet Military Area Command Lasa China.
Weiwei JiangDepartment of Dermatology 72nd Group Army Hospital of PLA Huzhou Zhejiang China.
Hang LiThe First Affiliated Hospital of Nanchang University Nanchang China.
Lei ZhangDepartment of Dermatology, Shaanxi Provincial People's Hospital The Third Affiliated Hospital of Xi'an Jiaotong University Xi'an China.
Hefu ZhenBGI Research Shenzhen China.
Shujun BaoDepartment of Respiratory and Critical Care Medicine Second Affiliated Hospital of Naval Medical University Shanghai China.
Xiong LiBGI Research Shenzhen China.
Yinuo LiuDepartment of Dermatology, Shanghai Key Laboratory of Molecular Medical Mycology, Shanghai Changzheng Hospital Naval Medical University Shanghai China.
Xianzhen ChenCentral Hospital Affiliated to Shandong First Medical University Jinan China.
Jinxia DuDepartment of Dermatology, Shanghai Key Laboratory of Molecular Medical Mycology, Shanghai Changzheng Hospital Naval Medical University Shanghai China.
Jingjing XiaState Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, and Human Phenome Institute Fudan University Shanghai China.
Jiucun WangState Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, and Human Phenome Institute Fudan University Shanghai China.
Ruijin GuoBGI Research Shenzhen China.
Yuzhe SunBGI Research Shenzhen China.
Bo PanDepartment of Dermatology, Shanghai Key Laboratory of Molecular Medical Mycology, Shanghai Changzheng Hospital Naval Medical University Shanghai China.
Wenzhi LeiDepartment of Dermatology, Shanghai Key Laboratory of Molecular Medical Mycology, Shanghai Changzheng Hospital Naval Medical University Shanghai China.
Liang XiaoBGI Research Shenzhen China.
Jin ZhaoDepartment of Dermatology, Shanghai Key Laboratory of Molecular Medical Mycology, Shanghai Changzheng Hospital Naval Medical University Shanghai China.
Xin JinBGI Research Shenzhen China.
Wenwei ZhangBGI Research Shenzhen China.
Xiaogang LiuDepartment of Dermatology, Shanghai Key Laboratory of Molecular Medical Mycology, Shanghai Changzheng Hospital Naval Medical University Shanghai China.
Jian WangBGI Research Shenzhen China.
Min ChenYueyang Hospital of Integrated Traditional Chinese and Western Medicine Shanghai University of Traditional Chinese Medicine Shanghai China.
Wanqing LiaoDepartment of Dermatology, Shanghai Key Laboratory of Molecular Medical Mycology, Shanghai Changzheng Hospital Naval Medical University Shanghai China.
Wenjie FangDepartment of Dermatology, Shanghai Key Laboratory of Molecular Medical Mycology, Shanghai Changzheng Hospital Naval Medical University Shanghai China.
Chao NieBGI Research Shenzhen China.
Weihua PanDepartment of Dermatology, Shanghai Key Laboratory of Molecular Medical Mycology, Shanghai Changzheng Hospital Naval Medical University Shanghai China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Comprehensive reference genomes are needed for the classification and functional characterization of the human skin microbiota. Here, we established human skin microbiome genome (HSMG) and protein (HSMP) catalogs by integrating 739 newly sequenced and 2,520 published samples, along with two published microbial genome catalogs. The HSMG includes 3547 prokaryotic species, of which 1556 (43.87%) are unidentified, and the HSMP contains 39,283,339 nonredundant proteins, with 64.8% of which are poorly characterized. Using the HSMG as a reference, we identified distinct features and biogeographical traits of the skin microbiome in plateau adults, revealing significant differences between sebaceous and dry skin, with 1784 of 3547 inferred prokaryotes showing considerable variation. Additionally, host characteristics, skincare, and daylight habits were found to shape the skin microbiome. This work expands our understanding of the diversity of uncultured skin bacteria and provides a comprehensive characterization of the human skin microbiome in plateau environments.

Indexed as

gene cataloghighlandhost phenotypemicrobiotaskin environment

Identifiers

PMID41675154
PMCPMC12806276

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.