Evidence map›Paper›PMID 41675130›Full record

ArticleFrontiers in aging neuroscience2026

Feasibility randomized controlled trial of a home-based support program for family caregivers of people with Alzheimer's disease.

Hongli Liu, Yuanli Jiang, Jiajia Chen, Wenqing Pan, Ping Ju, Ling Li, Li Zhang, Yunxing Cao, YuHang Zhu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in aging neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hongli Liu *Department of Critical Care Medicine, Chongqing General Hospital, Chongqing University, Chongqing, China.
Yuanli Jiang *Department of Geriatrics, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China.
Jiajia ChenNursing School of Zunyi Medical University, Zunyi, Guizhou, China.
Wenqing PanNursing School of Zunyi Medical University, Zunyi, Guizhou, China.
Ping JuDepartment of Critical Care Medicine, Chongqing General Hospital, Chongqing University, Chongqing, China.
Ling LiDepartment of Critical Care Medicine, Chongqing General Hospital, Chongqing University, Chongqing, China.
Li ZhangDiscipline Inspection and Supervision Office of Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China.
Yunxing CaoDepartment of Critical Care Medicine, Chongqing General Hospital, Chongqing University, Chongqing, China.
YuHang ZhuEarly Clinical Research Ward, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aimed to develop and preliminarily evaluate the feasibility of a home-based care program for family caregivers of individuals with Alzheimer's disease (AD). Methods: We developed a home-based intervention for AD caregivers through systematic literature review and two-round Delphi consensus (18 experts; authority coefficients 0.88-0.91). This feasibility randomized controlled trial enrolled 61 primary caregivers and assigned them to either an experimental group ( Results: The Delphi process achieved strong expert consensus. Post-intervention, caregivers in the intervention group demonstrated significant improvements in AD knowledge scores, anxiety reduction, and psychological domain QOL-AD scores compared to baseline ( Conclusion: The home-based care program proved feasible and effective in enhancing AD caregiver knowledge and mental health outcomes. These promising findings support the need for larger-scale efficacy trials to further validate clinical utility.

Indexed as

Alzheimer’s diseasefamily caregivershealth-related quality of lifehome carerandomized controlled trial

Identifiers

PMID41675130
PMCPMC12886407

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.