ArticleThe journal of allergy and clinical immunology. Global2026
Probiotics for pediatric atopic dermatitis: A systematic review and meta-analysis of randomized controlled trials.
Article in The journal of allergy and clinical immunology. Global, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- The Gut-Brain-Skin Axis: Systemic Effects of Functional Ingredients in Healthy Skin Aging.International journal of molecular sciences · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Atopic dermatitis is a prevalent chronic inflammatory skin disease in children and the severity of the disease can be affected by modulation of gut microbiota through probiotics. Nonetheless, the clinical trial outcomes on the effectiveness of probiotics in child atopic dermatitis are inconclusive. Objective: We sought to compare the effects of using probiotics in comparison with placebo in children/adolescents with eczema/atopic dermatitis. Methods: We searched PubMed/MEDLINE, Google Scholar, and Cochrane Library from inception to March 2025. Statistical analyses were done in Review Manager version 5.4.1 (The Nordic Cochrane Centre, Copenhagen, Denmark). Pooling the trials using a fixed effect yielded standard mean difference (SMD) with 95% CI. Results: A total of 13 randomized controlled trials were used. SCORing Atopic Dermatitis (SCORAD) was used for assessing the efficacy of probiotics on atopic dermatitis. Subgroup analysis demonstrated a statistically nonsignificant difference in SCORAD within the first 2 months of the treatment (SMD, -0.04 [95% CI, -0.24 to 0.16]; Conclusions: Analysis found that probiotics can improve patient-reported quality of life in the short-term but not clinical results. However, SCORAD varies considerably over time and paucity of long-term follow-up data makes it difficult to determine the long-term clinical value of probiotics.
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