Evidence map›Paper›PMID 41675010›Full record

ReviewTranslational breast cancer research : a journal focusing on translational research in breast cancer2026

Maria Florencia Illia, Giuliana Colucci, Andres Rodriguez Mignola, Mariana Eiben, Angeles María Ballester, Natalia Zeff, Fernando Paesani, Gabriel Crimi, Francisco Von Stecher, Maximo de la Vega and 2 more

Abstract readReview
In one paragraph

Review in Translational breast cancer research : a journal focusing on translational research in breast cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Maria Florencia IlliaMedical Oncology Department, Breast and Gynecological Tumors Unit, Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno" (CEMIC), Buenos Aires, Argentina.
Giuliana ColucciMedical Oncology Department, Breast and Gynecological Tumors Unit, Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno" (CEMIC), Buenos Aires, Argentina.
Andres Rodriguez MignolaRadiotherapy Department, Breast and Gynecological Tumors Unit, Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno" (CEMIC), Buenos Aires, Argentina.
Mariana EibenPathology Department, Breast and Gynecological Tumors Unit, Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno" (CEMIC), Buenos Aires, Argentina.
Angeles María BallesterGynecology Department, Breast and Gynecological Tumors Unit, Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno" (CEMIC), Buenos Aires, Argentina.
Natalia ZeffGynecology Department, Breast and Gynecological Tumors Unit, Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno" (CEMIC), Buenos Aires, Argentina.
Fernando PaesaniGynecology Department, Breast and Gynecological Tumors Unit, Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno" (CEMIC), Buenos Aires, Argentina.
Gabriel CrimiGynecology Department, Breast and Gynecological Tumors Unit, Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno" (CEMIC), Buenos Aires, Argentina.
Francisco Von StecherGynecology Department, Breast and Gynecological Tumors Unit, Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno" (CEMIC), Buenos Aires, Argentina.
Maximo de la VegaMedical Oncology Department, Breast and Gynecological Tumors Unit, Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno" (CEMIC), Buenos Aires, Argentina.
Florencia PerazzoMedical Oncology Department, Breast and Gynecological Tumors Unit, Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno" (CEMIC), Buenos Aires, Argentina.
Pablo MandóMedical Oncology Department, Breast and Gynecological Tumors Unit, Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno" (CEMIC), Buenos Aires, Argentina.ORCID https://orcid.org/0000-0001-8387-9011

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objective: Breast cancer (BC) remains the most prevalent malignancy in women globally, with hormone receptor-positive (HR Methods: A narrative review was conducted using PubMed, Google Scholar, and abstracts from major oncology congresses [European Society for Medical Oncology (ESMO), American Society of Clinical Oncology (ASCO), and San Antonio Breast Cancer Symposium]. The search employed terms including "CDK inhibitors", " Key Content and Findings: The review synthesizes data from retrospective studies and clinical trials, revealing consistent trends of shorter PFS and OS in gBRCAm patients treated with CDK4/6i compared to wild-type counterparts. Key mechanisms implicated include co-occurring Conclusions: This review underscores the need for prospective studies to clarify the prognostic and predictive role of gBRCAm in CDK4/6i-treated HR

Indexed as

BRCAbreast cancer (BC)Cyclin-dependent kinase 4/6 inhibitors (CDK4/6i)

Identifiers

PMID41675010
PMCPMC12885774

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.