Evidence map›Paper›PMID 41674888›Full record

ArticleClinical case reports2026

Recurrent Hypoglycaemia Leading to Early Diagnosis of Septo-Optic Dysplasia in a Small-for-Gestational-Age Infant-A Case Report.

Yuan Rui Leon Tan, Xiaoao Dong, Ngee Lek, Suresh Chandran, Odattil Geetha

Abstract read
In one paragraph

Article in Clinical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yuan Rui Leon TanDepartment of Neonatology KK Women's and Children's Hospital Singapore.ORCID https://orcid.org/0000-0002-6656-4701
Xiaoao DongDepartment of Neonatology KK Women's and Children's Hospital Singapore.ORCID https://orcid.org/0000-0001-8116-4135
Ngee LekDepartment of Pediatrics KK Women's and Children's Hospital Singapore.
Suresh ChandranDepartment of Neonatology KK Women's and Children's Hospital Singapore.ORCID https://orcid.org/0000-0001-5961-7441
Odattil GeethaDepartment of Neonatology KK Women's and Children's Hospital Singapore.ORCID https://orcid.org/0000-0002-8301-9262

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Septo-optic dysplasia (SOD) is a rare condition with highly heterogenous clinical manifestations and can be a diagnostic challenge. It can present with pituitary hormone deficiencies, growth failure, visual impairment, and neurological symptoms. SOD can be diagnosed at different time points-from the prenatal period to childhood. Our team cared for a baby girl who presented with recurrent hypoglycaemia, conjugated hyperbilirubinemia, and hormonal deficiencies, prompting investigations that resulted in an early diagnosis of SOD. This case report highlights the importance of considering neuroimaging to exclude septo-optic dysplasia in term infants with recurrent hypoglycaemia, low cortisol, and growth hormone levels, as timely diagnosis with early hormone replacement reduces long-term morbidities.

Indexed as

case reportcholestasishypopituitarismneonaterecurrent hypoglycaemiasepto‐optic dysplasia

Identifiers

PMID41674888
PMCPMC12886194

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.