Evidence map›Paper›PMID 41674816›Full record

ArticleResearch square2026

Cloning and functional verification of endogenous U6 promoters for developing an efficient CRISPR/Cas9-mediated genome editing system in kenaf (Hibiscus cannabinus L.).

Shaolian Jiang, Fangzhou Chen, Haixiong Ma, Siyan Wu, Xin Tang, Xueqing Pan, Qin Li, Aifen Tao, Jiantang Xu, Jianmin Qi and 3 more

Abstract readPreprint
In one paragraph

Article in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Shaolian JiangFujian Agriculture and Forestry University.
Fangzhou ChenFujian Agriculture and Forestry University.
Haixiong MaFujian Agriculture and Forestry University.
Siyan WuFujian Agriculture and Forestry University.
Xin TangFujian Agriculture and Forestry University.
Xueqing PanFujian Agriculture and Forestry University.
Qin LiFujian Agriculture and Forestry University.
Aifen TaoFujian Agriculture and Forestry University.
Jiantang XuFujian Agriculture and Forestry University.
Jianmin QiFujian Agriculture and Forestry University.
Pingping FangFujian Agriculture and Forestry University.
Jikang ChenChinese Academy of Agricultural Sciences.
Liwu ZhangFujian Agriculture and Forestry University.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The U6 promoter plays a pivotal role in the CRISPR/Cas9 system by driving the transcription of single guide RNA (sgRNA), which directs Cas9 to achieve precise genome editing. Endogenous U6 promoters typically exhibit superior transcriptional activation efficiency compared to exogenous counterparts, thereby enhancing the efficacy of genome editing. However, the endogenous U6 promoter in kenaf (

Indexed as

CRISPR/Cas9gene editingKenafU6 promoter

Identifiers

PMID41674816
PMCPMC12889822

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.