Evidence map›Paper›PMID 41674802›Full record

ArticleEnvironmental epidemiology (Philadelphia, Pa.)2026

Blood lead levels in children and soil lead contamination in a former mining area in Germany.

Lea John, Katja Radon, Walter Schmotz, Finn Sonnemann, Michael Hoopmann, Nathalie Costa Pinheiro, Martin Hepp, Stefan Rakete, Dennis Nowak, Laura Wengenroth

Abstract read
In one paragraph

Article in Environmental epidemiology (Philadelphia, Pa.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lea JohnInstitute and Clinic for Occupational, Social and Environmental Medicine, LMU University Hospital, LMU Munich, Munich, Germany.ORCID https://orcid.org/0009-0004-3445-1309
Katja RadonInstitute and Clinic for Occupational, Social and Environmental Medicine, LMU University Hospital, LMU Munich, Munich, Germany.
Walter SchmotzDistrict of Goslar, Department of Construction & Environment - Soil Protection and Waste Monitoring, Goslar, Germany.
Finn SonnemannDistrict of Goslar, Department of Construction & Environment - Soil Protection and Waste Monitoring, Goslar, Germany.
Michael HoopmannPublic Health Agency of Lower Saxony, NLGA, Hanover, Germany.
Nathalie Costa PinheiroPublic Health Agency of Lower Saxony, NLGA, Hanover, Germany.
Martin HeppDistrict of Goslar, Department of Public Health Services, Goslar, Germany.
Stefan RaketeInstitute and Clinic for Occupational, Social and Environmental Medicine, LMU University Hospital, LMU Munich, Munich, Germany.
Dennis NowakInstitute and Clinic for Occupational, Social and Environmental Medicine, LMU University Hospital, LMU Munich, Munich, Germany.
Laura WengenrothInstitute and Clinic for Occupational, Social and Environmental Medicine, LMU University Hospital, LMU Munich, Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Lead-contaminated soils in former mining areas can pose an environmental hazard for decades. In the former mining district of Goslar, Germany, where mining ceased in 1988, soil lead exposure remains a public health concern, with median soil lead concentrations reaching up to 1,500 mg/kg in residential areas. Children are particularly vulnerable to lead exposure due to physiological and behavioral factors. This study aimed to assess blood lead levels (BLLs) in children and identify key exposure pathways. Methods: In a cross-sectional study conducted in 2023/24, BLLs were measured in 310 5-7-year-old children. Guardians provided information on potential exposure pathways, including handwashing behavior, hand-to-mouth contact, consumption of homegrown/foraged food, outdoor activity, and secondhand smoke. Children's locations of residence and recreation were assessed, and soil contamination data were available. Factors were analyzed using bivariate comparisons and adjusted linear regression model. Results: The BLL geometric mean was 22.7 μg/L. Of the children, 51% exceeded the German reference values (19/22 μg/L girls/boys), and 24% exceeded the US reference value (35 μg/L). Thirteen percent had BLLs above 50 μg/L, the World Health Organization benchmark for preventive action. Soil contamination emerged as the main exposure pathway. Children living in very highly contaminated areas had BLLs 29% higher (95% CI: 7%, 56%) than those in the least contaminated areas. Conclusions: These results emphasize the importance of continuing and strengthening preventive measures to reduce lead exposure and intake. Given similar historical contamination in other regions, more extensive environmental assessments and targeted interventions are required to protect children's health in former mining areas worldwide.

Indexed as

Blood lead level (BLL)ChildrenEnvironmental epidemiologyGermanyLead exposureMining

Identifiers

PMID41674802
PMCPMC12889315

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.