ArticleFrontiers in nutrition2025
Association between the CHG index and cardiometabolic multimorbidity: a nationwide prospective cohort and multi-community cross-sectional study.
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- The cholesterol, high-density lipoprotein, and glucose index and its derived indices predict cardiometabolic multimorbidity development and progression in metabolic dysfunction-associated steatotic liver disease individuals: a prospective cohort study.Cardiovascular diabetology · 2026Article
- Polysaccharide-driven gut microbial metabolism in neurodegenerative brain diseases: from SCFAs and tryptophan catabolites to neuroinflammatory regulation.Metabolic brain disease · 2026Review
- Exploratory mediation analysis of body roundness index in the nonlinear association between CHG index and metabolic dysfunction-associated steatotic liver disease among non-diabetic adults.Frontiers in nutrition · 2026Article
- Cholesterol, high-density lipoprotein, and glucose (CHG) index and incident impaired fasting glucose in Chinese adults: a retrospective longitudinal cohort study.Frontiers in nutrition · 2026Article
- Association of the cholesterol-high-density lipoprotein-glucose index with coronary atherosclerotic burden in patients with coronary artery disease.Frontiers in nutrition · 2026Article
- The association between HbA1c/HDL-C ratio and cardiometabolic multimorbidity among middle-aged and older adults: data from two national prospective cohorts in the United Kingdom and United States.Frontiers in nutrition · 2026Article
- Cumulative exposure and patterns of the cholesterol-HDL-C-glucose index and risk of new-onset cardiometabolic multimorbidity: 9-year longitudinal evidence from CHARLS.Frontiers in nutrition · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Cardiometabolic multimorbidity (CMM) is a growing public health challenge, with limited practical biomarkers available for early detection. Given the established relationship between impaired lipid as well as glucose homeostasis and CMM, this study aims to examine the association between the cholesterol, high-density lipoprotein, and glucose (CHG) index and CMM risk. Methods: A nationwide prospective cohort (CHARLS, 2011-2018; Results: In the CHARLS cohort, 491 (5.8%) individuals developed incident CMM over 7 years of follow-up. CHG levels were significantly elevated in patients with CMM ( Conclusion: An elevated CHG index is independently associated with an increased risk of CMM across both prospective and cross-sectional studies. It serves as a robust and reproducible predictor for the early identification of CMM in diverse Chinese populations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.