Evidence map›Paper›PMID 41674791›Full record

ArticleAJOG global reports2026

Relation between epidural analgesia and perinatal outcomes on Robson class 2a.

Serena Lecis, Giulia Bonfiglioli, Francesco Cannistrà, Sara Verra, Lucia Lisotti, Letizia Ramovecchi, Antonio Saddò, Giuseppe Chiossi, Riccardo Cuoghi Costantini, Roberto D'Amico and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AJOG global reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Serena LecisObstetrics and Gynecology Unit, Mother-Infant and Adult Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Largo del Pozzo 71, 41124 Modena, Italy (Lecis, Bonfiglioli, Cannistrà, Verra, Lisotti, Ramovecchi, Saddò, Chiossi, Lazzarin, Neri, La Marca, and Monari).
Giulia BonfiglioliObstetrics and Gynecology Unit, Mother-Infant and Adult Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Largo del Pozzo 71, 41124 Modena, Italy (Lecis, Bonfiglioli, Cannistrà, Verra, Lisotti, Ramovecchi, Saddò, Chiossi, Lazzarin, Neri, La Marca, and Monari).
Francesco CannistràObstetrics and Gynecology Unit, Mother-Infant and Adult Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Largo del Pozzo 71, 41124 Modena, Italy (Lecis, Bonfiglioli, Cannistrà, Verra, Lisotti, Ramovecchi, Saddò, Chiossi, Lazzarin, Neri, La Marca, and Monari).
Sara VerraObstetrics and Gynecology Unit, Mother-Infant and Adult Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Largo del Pozzo 71, 41124 Modena, Italy (Lecis, Bonfiglioli, Cannistrà, Verra, Lisotti, Ramovecchi, Saddò, Chiossi, Lazzarin, Neri, La Marca, and Monari).
Lucia LisottiObstetrics and Gynecology Unit, Mother-Infant and Adult Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Largo del Pozzo 71, 41124 Modena, Italy (Lecis, Bonfiglioli, Cannistrà, Verra, Lisotti, Ramovecchi, Saddò, Chiossi, Lazzarin, Neri, La Marca, and Monari).
Letizia RamovecchiObstetrics and Gynecology Unit, Mother-Infant and Adult Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Largo del Pozzo 71, 41124 Modena, Italy (Lecis, Bonfiglioli, Cannistrà, Verra, Lisotti, Ramovecchi, Saddò, Chiossi, Lazzarin, Neri, La Marca, and Monari).
Antonio SaddòObstetrics and Gynecology Unit, Mother-Infant and Adult Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Largo del Pozzo 71, 41124 Modena, Italy (Lecis, Bonfiglioli, Cannistrà, Verra, Lisotti, Ramovecchi, Saddò, Chiossi, Lazzarin, Neri, La Marca, and Monari).
Giuseppe ChiossiObstetrics and Gynecology Unit, Mother-Infant and Adult Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Largo del Pozzo 71, 41124 Modena, Italy (Lecis, Bonfiglioli, Cannistrà, Verra, Lisotti, Ramovecchi, Saddò, Chiossi, Lazzarin, Neri, La Marca, and Monari).
Riccardo Cuoghi CostantiniUniversity of Modena and Reggio Emilia, Department of Medical and Surgical Sciences, Largo del Pozzo 71, 41124 Modena, Italy (Cuoghi Costantini).
Roberto D'AmicoCenter of Statistic, Department of Medical and Surgical Sciences, UNIMORE, 41224 Modena, Italy (D'Amico).
Sara LazzarinDepartment of Intensive Care Unit and Anesthesiology University of Modena and Reggio Emilia, Largo del Pozzo 71, 41124 Modena, Italy (Lazzarin).
Fabio FacchinettiResearch Center in Environmental, Nutritional and Genetic Epidemiology (CREAGEN), Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Campi 287, 41125 Modena, Italy (Facchinetti).
Isabella NeriObstetrics and Gynecology Unit, Mother-Infant and Adult Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Largo del Pozzo 71, 41124 Modena, Italy (Lecis, Bonfiglioli, Cannistrà, Verra, Lisotti, Ramovecchi, Saddò, Chiossi, Lazzarin, Neri, La Marca, and Monari).
Lara DonnoAnesthesia and Intensive Care Unit, University of Modena and Reggio Emilia, Modena, Italy (Donno and Girardis).
Massimo GirardisAnesthesia and Intensive Care Unit, University of Modena and Reggio Emilia, Modena, Italy (Donno and Girardis).
Antonio La MarcaObstetrics and Gynecology Unit, Mother-Infant and Adult Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Largo del Pozzo 71, 41124 Modena, Italy (Lecis, Bonfiglioli, Cannistrà, Verra, Lisotti, Ramovecchi, Saddò, Chiossi, Lazzarin, Neri, La Marca, and Monari).
Francesca MonariObstetrics and Gynecology Unit, Mother-Infant and Adult Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Largo del Pozzo 71, 41124 Modena, Italy (Lecis, Bonfiglioli, Cannistrà, Verra, Lisotti, Ramovecchi, Saddò, Chiossi, Lazzarin, Neri, La Marca, and Monari).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

objectiveSTUDY

designA retrospective cohort study was conducted on every Robson class 2a individual who delivered from January 1, 2022, to December 31, 2023, at the University Hospital of Modena in the north of Italy. The primary outcome was the delivery mode (cesarean delivery, vaginal delivery, and operative vaginal delivery rates), and the secondary outcomes were the effect of epidural analgesia on the duration of labor, duration of the second stage of labor, Apgar score, and neonatal intensive care unit admission.

resultsOverall, 809 individuals were included in the final analysis, and 456 of them (56.4%) received epidural analgesia on request. Among individuals with and those without epidural analgesia, the cesarean delivery rate was 25% and 20.4% (

conclusionEpidural analgesia was among the factors that increased both the induction and second stage of delivery times. However, epidural analgesia did not impact the mode of delivery and perinatal outcomes in Robson class 2a individuals.

Indexed as

cesarean deliveryepidural analgesianulliparous individualsobstetrical anesthesiaperinatal outcomesRobson classification

Identifiers

PMID41674791
PMCPMC12886058

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.