ArticleCureus2026
An Evaluation of Common Carotid Artery Intima-Media Thickness in Patients With Acute Ischemic Stroke: A Case-Control Study.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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10 authors.
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Abstract
introductionStroke has major clinical and economic ramifications and is one of the world's top causes of morbidity and mortality. Over the past years, there has been an increasing trend in the occurrence of stroke in India. The association between increased common carotid artery intima-media thickness (CIMT) and stroke risk in India's general population has not been well studied. Thus, the purpose of this study is to evaluate, compare, and establish a relationship between the CIMT in acute ischemic stroke (AIS) patients and healthy individuals.
methodsThis prospective, observational, cross-sectional, and case-control study was conducted among patients admitted to the Departments of General Medicine and Neurology at a tertiary-care teaching hospital in Bengaluru, India. The study was conducted between March 2023 and March 2025 and included 50 patients. A total of 25 patients with AIS were included as cases, and 25 healthy individuals were included as controls. The carotid artery Doppler test was used to measure the CIMT. The hematological and biochemical parameters of all the study participants were measured using standard laboratory techniques.
resultsIn both groups, the majority of individuals were aged 50 years or older. The control group's mean age was 56.64 ± 10.03 years, compared to 54.40 ± 12.36 years in the case group (t = 0.70, p = 0.48). In contrast to the control group, which had 92% (23) male and 8% (two) female participants (chi-square (𝜒
conclusionsPatients with AIS have considerably higher CIMT, which supports its application as a noninvasive and affordable diagnostic modality for identifying people who are more likely to experience cerebrovascular episodes.
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