Evidence map›Paper›PMID 41674647›Full record

ArticlemedRxiv : the preprint server for health sciences2026

Top-Down Proteomics in the Assessment of Kidney Donor Quality: a novel approach to increased organ utilization.

Claudia Ctortecka, Dinesh Jaishankar, Pei Su, Che-Fan Huang, Indira Pla, Nathaniel Henning, Michael A R Hollas, Michelle A Callegari, Meredith E Taylor, Yu Min Lee and 8 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

Claudia CtorteckaChemistry of Life Processes Institute, Northwestern University, Evanston, IL.ORCID 0000-0002-6886-8936
Dinesh JaishankarDepartment of Surgery, Division of Organ Transplant, Feinberg School of Medicine, Northwestern University, Chicago, IL.
Pei SuProteomics Center of Excellence, Northwestern University, Evanston, IL.
Che-Fan HuangProteomics Center of Excellence, Northwestern University, Evanston, IL.ORCID 0000-0002-5799-1533
Indira PlaProteomics Center of Excellence, Northwestern University, Evanston, IL.
Nathaniel HenningProteomics Center of Excellence, Northwestern University, Evanston, IL.
Michael A R HollasProteomics Center of Excellence, Northwestern University, Evanston, IL.
Michelle A CallegariDepartment of Surgery, Division of Organ Transplant, Feinberg School of Medicine, Northwestern University, Chicago, IL.
Meredith E TaylorDepartment of Surgery, Division of Organ Transplant, Feinberg School of Medicine, Northwestern University, Chicago, IL.
Yu Min LeeDepartment of Surgery, Division of Organ Transplant, Feinberg School of Medicine, Northwestern University, Chicago, IL.
Amna DaudDepartment of Surgery, Division of Organ Transplant, Feinberg School of Medicine, Northwestern University, Chicago, IL.
David F PinelliDepartment of Surgery, Division of Organ Transplant, Feinberg School of Medicine, Northwestern University, Chicago, IL.
Vinayak RohanDepartment of Surgery, Division of Organ Transplant, Feinberg School of Medicine, Northwestern University, Chicago, IL.
Michael A CaldwellChemistry of Life Processes Institute, Northwestern University, Evanston, IL.
Eleonora ForteDivision of Nephrology, Department of Medicine, College of Medicine, University of Illinois Chicago, Chicago, IL.
Aniel SanchezProteomics Center of Excellence, Northwestern University, Evanston, IL.
Neil L KelleherChemistry of Life Processes Institute, Northwestern University, Evanston, IL.ORCID 0000-0002-8815-3372
Satish N NadigDepartment of Surgery, Division of Organ Transplant, Feinberg School of Medicine, Northwestern University, Chicago, IL.

Funding

Modulating endothelial cell immunometabolism and mitochondrial morphologyimplications for organ transplantationR01AI142079 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI NADIG, SATISH N · 2019 to 2023
$1.9M
NIAID NIH HHS R01 AI142079
6 · The paper itself

Abstract

Kidney transplantation faces a critical paradox: while thousands await organs, approximately 30% of potential deceased donor kidneys are discarded for various reasons, including

Indexed as

Cell SignalingKidney BiopsyKidney DonationProteomic AnalysisTransplantation

Identifiers

PMID41674647
PMCPMC12889773

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.