Evidence map›Paper›PMID 41674537›Full record

ReviewQuantitative biology (Beijing, China)2023

Quantitative functionalization of biosynthetic caged protein materials.

Quan Cheng, Xuan Wang, Xian-En Zhang, Chengchen Xu, Feng Li

Abstract readReview
In one paragraph

Review in Quantitative biology (Beijing, China), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Quan ChengCollege of Life Sciences and Health Wuhan University of Science and Technology Wuhan 430065 China.
Xuan WangCollege of Life Sciences and Health Wuhan University of Science and Technology Wuhan 430065 China.
Xian-En ZhangFaculty of Synthetic Biology Shenzhen Institute of Advanced Technology Chinese Academy of Sciences Shenzhen 518055 China.
Chengchen XuCollege of Life Sciences and Health Wuhan University of Science and Technology Wuhan 430065 China.
Feng LiState Key Laboratory of Virology Wuhan Institute of Virology Center for Biosafety Mega-Science Chinese Academy of Sciences Wuhan 430071 China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: As one of the representative protein materials, protein nanocages (PNCs) are self-assembled supramolecular structures with multiple advantages, such as good monodispersity, biocompatibility, structural addressability, and facile production. Precise quantitative functionalization is essential to the construction of PNCs with designed purposes. Results: With three modifiable interfaces, the interior surface, outer surface, and interfaces between building blocks, PNCs can serve as an ideal platform for precise multi-functionalization studies and applications. This review summarizes the currently available methods for precise quantitative functionalization of PNCs and highlights the significance of precise quantitative control in fabricating PNC-based materials or devices. These methods can be categorized into three groups, genetic, chemical, and combined modification. Conclusion: This review would be constructive for those who work with biosynthetic PNCs in diverse fields.

Indexed as

chemical modificationfunctionalizationgenetic modificationprotein nanocagesvirus‐like particles

Identifiers

PMID41674537
PMCPMC12807042

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.