Evidence map›Paper›PMID 41674163›Full record

ArticleNicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco2026

Barriers and facilitators to enforcing E-cigarette regulations for online sales.

Sangah Clara Lee, Ginny Chadwick, Gina R Kruse, Maeve Stover, Luke I Haqq, Boram Lee, Douglas E Levy

Abstract read
In one paragraph

Article in Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sangah Clara LeeDepartment of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, MA, USA.ORCID 0000-0001-6691-7688
Ginny ChadwickMongan Institute Health Policy Research Center and Tobacco Research and Treatment Center, Massachusetts General Hospital, Boston, MA, USA.ORCID 0000-0001-7977-3054
Gina R KruseDivision of General Internal Medicine, University of Colorado School of Medicine, Aurora, CO, USA.
Maeve StoverMongan Institute Health Policy Research Center and Tobacco Research and Treatment Center, Massachusetts General Hospital, Boston, MA, USA.
Luke I HaqqPublic Health Law Center, Mitchell Hamline School of Law, St. Paul, MN, USA.
Boram LeeDepartment of Health Convergence, Ewha Womans University, Seoul, South Korea.
Douglas E LevyMongan Institute Health Policy Research Center and Tobacco Research and Treatment Center, Massachusetts General Hospital, Boston, MA, USA.ORCID 0000-0001-9446-7899

Funding

Assessing the impact of vaping control policies at the school, local and state levelsR01DA054935 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI Douglas Levy · 2022 to 2026
$3.8M
The Harvard Chan Education Program in Cancer Prevention and ControlT32CA057711 · NCI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Karen M. Emmons, ANNE LINDSAY FRAZIER · 2019 to 2026
$3.3M
NCI NIH HHS T32 CA057711NIDA NIH HHS R01 DA054935
6 · The paper itself

Abstract

introductionOnline sales of e-cigarettes challenge the enforcement of state tobacco control (TC) policies. Using key informant (KI) interviews, we examined barriers and facilitators to implementing TC policies in the context of e-cigarettes sold online.

methodsFrom April 2023 to December 2024, we invited state representatives from all 50 states and the District of Columbia to participate in KI interviews. Guided by Bullock's (2021) policy implementation framework, we examined licensure, minimum legal sales age, flavor bans, and taxation. Data were analyzed using team-based, iterative coding.

resultsWe conducted 74 semi-structured interviews with 90 KIs across 41 states, of which online sales emerged as a key theme in 41 interviews with 60 KIs across 34 states. KIs noted how online sales interacted with existing legal frameworks and enforcement methods, often creating challenges, including jurisdictional ambiguity over out-of-state or international sellers, limited capacity to monitor the emergence of new online sellers, statutory language not designed for digital commerce, supply chain ambiguity, and logistical difficulties in conducting online decoy buys. KIs noted several potential enforcement facilitators, including the Prevent All Cigarette Trafficking Act (e.g., monthly delivery sales reports), consumer complaint systems, internet surveillance, directories of products authorized for sale, and interstate coordination of data sharing. Some states pursued legal action against online retailers using consumer protection laws.

conclusionsOnline e-cigarette sales present a regulatory challenge for TC implementation, requiring policy adaptation, cross-jurisdictional coordination, enhanced monitoring, and research to guide effective regulation of the digital marketplace. IMPLICATIONS: This work may inform future policy and enforcement strategies by highlighting the unique regulatory gaps created by online e-cigarette sales. Traditional tobacco control mechanisms, developed initially for brick-and-mortar retailers, are not well-suited to the rapidly evolving online marketplace. Strengthening the utility of the Prevent All Cigarette Trafficking Act by integrating reporting, shipping, and tax compliance data into state licensure, minimum legal sales age, flavor, and tax enforcement could help states more effectively detect noncompliant sellers. Complementary measures such as robust age verification, clearer statutory definitions, and partnerships with carriers, financial institutions, and technology platforms are critical to adapting tobacco control to the realities of digital commerce.

Indexed as

CommerceElectronic Nicotine Delivery SystemsInternetHumansLicensureTaxesTobacco ControlUnited Statese-cigarettes/vapinglegislation/regulations/policiestobacco regulatory science

Identifiers

PMID41674163
PMCPMC12958444

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.