Evidence map›Paper›PMID 41674061›Full record

ArticleJournal of microbiology and biotechnology2026

Beneficial Effects of

Sol Lee, Eun Jeoung Lee, Chang Won Ahn, Han-Oh Park, Changmin Lee

Erratum issuedAbstract read
In one paragraph

Article in Journal of microbiology and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Sol LeeAceBiome Inc., Seoul 06164, Republic of Korea.
Eun Jeoung LeeAceBiome Inc., Seoul 06164, Republic of Korea.
Chang Won AhnAceBiome Inc., Seoul 06164, Republic of Korea.
Han-Oh ParkAceBiome Inc., Seoul 06164, Republic of Korea.
Changmin LeeAceBiome Inc., Seoul 06164, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increased ultraviolet (UV) exposure due to ozone depletion significantly affects human skin health. Recent skin research has been exploring various interventions to counteract the effects of UV-induced photoaging. UV directly affects skin components such as collagen and natural moisturizing factors (NMF), which are essential for the skin's structural integrity and hydration. Recent studies on the gut-skin axis have shown that certain probiotic strains could significantly improve skin aging. So, we examined the effect of ABF21013 on pro-collagen production and hyaluronic acid secretion using skin tissue from UVB-induced mice treated with ABF21013. Our findings reveal that ABF21013 reduced the total number of wrinkles and skin thickness by up-regulating MMP degradation and pro-collagen biosynthesis. These results indicate that ABF21013 can regulate wrinkle formation through the enhancement of collagen. Additionally, we observed downregulated transepidermal water loss (TEWL) regarding skin moisturizing. We also detected increased expression of EGFR ligands, AMPKα, hyaluronan synthase (HAS) -1/-2, and filaggrin. We have proved that ABF21013 can protect the skin barrier by activating the EGFR signaling pathway. Taken together, these results demonstrated that

Indexed as

ErbB ReceptorsLacticaseibacillus paracaseiMatrix MetalloproteinasesProbioticsSkinSkin AgingAnimalsCollagenFemaleFilaggrin ProteinsHumansHyaluronan SynthasesHyaluronic AcidIntermediate Filament ProteinsMiceSignal TransductionCollagenEGFR protein, mouseErbB ReceptorsFilaggrin ProteinsFLG protein, humanHas2 protein, mouseHyaluronan SynthasesHyaluronic AcidIntermediate Filament ProteinsMatrix MetalloproteinasesEGFR SignalingExtracellular matrix (ECM)Hyaluronic acid (HA)Skin-gut axisUVB-induced damage

Identifiers

PMID41674061
PMCPMC12935501

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.