Evidence map›Paper›PMID 41673813›Full record

ArticleBMC public health2026

Native Hawaiian and Pacific Islander community-led survey on COVID-19 and willingness to participate in clinical trials.

Mona AuYoung, Keni Lasitani, Tana Lepule, Raynald Samoa, Nia Aitaoto

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mona AuYoungDavid Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA. MAuYoung@mednet.ucla.edu.
Keni LasitaniDavid Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Tana LepuleUniversity of California San Diego School of Medicine, San Diego, CA, USA.
Raynald SamoaCity of Hope National Medical Center, Duarte, CA, USA.
Nia AitaotoPacific Islander Center of Primary Care Excellence, San Leandro, CA, USA.

Funding

NHLBI Maternal Morbidity and Mortality (3M) Administrative Coordinating CenterOT2HL158287 · NHLBI · WESTAT, INC. · PI Chanza Baytop · 2020 to 2026
$433.8M
NIH HHS OT2HL158287
6 · The paper itself

Abstract

backgroundNative Hawaiians and Pacific Islanders (NHPIs) have historically been erased from public health and research data due to smaller population size and mis-categorization. This became a bigger problem during the COVID-19 pandemic where NHPIs were disproportionately impacted, yet this was largely hidden because NHPI data were grouped with Asian Americans or aggregated into the Other category. This study assesses the impact of COVID-19 on the NHPI community as well as their willingness to participate in clinical trials.

methodsThis cross-sectional study took place between April 2021 and January 2022. Individuals in San Diego County who identified as NHPI were eligible to complete the survey on behalf of their households. The primary outcomes are willingness to get vaccinated and to participate in clinical trials as measured by Likert scales.

resultsOf the 130 households (representing 605 individuals) that responded to the survey, the majority were Samoan (53%) and Chamorro (30%) with an average household size of 4.6 individuals. Most (88%) households had one or more essential workers. The biggest COVID-19 challenges for respondents were paying for rent or food, caring for sick relatives, and dealing with lost jobs. Nearly half of households relied on support from community-based organizations, especially for meals/groceries, emotional/spiritual/mental health support and COVID-19 resources/vaccines. There was a stark contrast between willingness to get vaccinated (67% had gotten their second vaccine dose) and willingness to participate in a clinical trial (56% not at all likely to participate). This paralleled the difference in having a great deal of trust in COVID-19 information from doctors (69%) compared to researchers (37%).

conclusionsThis paper describes the gap between policy and practice, specifically a mismatch of available resources (for example, personal protective equipment and free COVID-19 tests from workplaces and the federal government) to those at disproportionate risk of exposure and severe outcomes during a pandemic. It also discusses the benefits of having local community-based organizations to help fill gaps in the public health system. Future research is needed to explore the reasons for lower levels of trust in researchers and less willingness to participate in clinical trials, which has implications for equity in research.

Indexed as

Clinical Trials as TopicCOVID-19Native Hawaiian or Pacific IslanderAdultAgedCaliforniaCOVID-19 VaccinesCross-Sectional StudiesFemaleHumansMaleMiddle AgedPacific Island PeopleSurveys and QuestionnairesCOVID-19 VaccinesClinical trialsCommunity-based organizationsDiversityNative hawaiians and pacific islandersTrust

Identifiers

PMID41673813
PMCPMC12998361

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.