Evidence map›Paper›PMID 41673784›Full record

ArticleThe Veterinary record2026

Cystitis in guinea pigs (Cavia porcellus): Clinical findings and treatment outcomes.

Anika Mische, Kerstin Müller

Abstract read
In one paragraph

Article in The Veterinary record, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Anika MischeSmall Animal Clinic, Freie Universität Berlin, Berlin, Germany.ORCID https://orcid.org/0009-0006-6116-0640
Kerstin MüllerSmall Animal Clinic, Freie Universität Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0003-0618-6961

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis retrospective study examined the incidence, diagnostic methods, bacterial isolates, treatments and outcomes associated with cystitis in guinea pigs presented at a single clinic between 2009 and 2022.

methodsThe clinic's medical records database was reviewed using easyvet software to identify cases eligible for inclusion in the study. Inclusion criteria were leukocyturia and/or bacteriuria, with at least one radiographic and one ultrasonographic examination. Culture-confirmed cases with imaging-based diagnoses were also included.

resultsForty-six guinea pigs met the inclusion criteria. Clinical signs included haematuria (n = 12), incontinence (n = 10), stranguria (n = 5), abdominal discomfort (n = 6), inappetence (n = 8), weight loss (n = 4) and apathy (n = 3). Ultrasonography revealed ascites (28%), peritonitis (33%) and urinary bladder sludge (63%). Bacterial isolates were obtained in 21 cases, with Corynebacterium renale (50%) and Staphylococcus spp. (21%) being most frequently isolated. Resistance to fluoroquinolones was observed, while the highest susceptibility was observed with chloramphenicol. Recurrence/reinfection occurred in 37% of cases, and the median survival time was 249 days. Euthanasia owing to severe cystitis was required in 24% of cases. LIMITATIONS: The absence of urine culture in 25 cases reduced diagnostic certainty. The retrospective nature limited full assessment of antimicrobial resistance patterns.

conclusionCystitis involving C. renale was linked to chronic progression and high recurrence rates.

Indexed as

CystitisRodent DiseasesAnimalsAnti-Bacterial AgentsFemaleGuinea PigsIncidenceMaleRetrospective StudiesTreatment OutcomeAnti-Bacterial Agents

Identifiers

PMID41673784
PMCPMC13330707

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.