ArticleBMC medicine2026
Particulate matter and respiratory health in middle-aged and older adults: disentangling size-fractionated and constituent-specific effects under China's clean-air policies.
Article in BMC medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Funding
Abstract
backgroundParticulate matter (PM) with distinct physicochemical properties may drive differential respiratory health risks. We investigated associations of long-term exposure to size- and constituent-specific PM with chronic respiratory diseases (CRDs) and evaluated respiratory benefits linked to PM composition changes under China's air control policies.
methodsA prospective cohort of 2100 adults (baseline mean age, 57.2 years) in Guangzhou, China, was followed between 2008 and 2021. Residential exposure to size-fractionated PM (PM
resultsApproximately, 7.7% (n = 162/2100) of participants developed any CRD during a median follow-up of 9.0 years. Increased exposure to PM
conclusionsPM-associated CRD risks were largely attributed to shared variances of PM across size fractions and toxic effects of constituents, particularly sulfate. Targeted emission controls for toxic PM sources may mitigate respiratory health risks.
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