Evidence map›Paper›PMID 41673618›Full record

ArticleBMC pregnancy and childbirth2026

Fetal renal artery Doppler as a predictor of impaired perfusion in preeclampsia.

Samin Alihosseini, Parvin Hakimi, Shahab Abdi, Farid Pakizeh, Elham Eghbali

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Article in BMC pregnancy and childbirth, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

5 authors.

Samin AlihosseiniMedical Radiation Sciences Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Parvin HakimiWomen's Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Shahab AbdiMedical Radiation Sciences Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Farid PakizehMedical Radiation Sciences Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Elham EghbaliMedical Radiation Sciences Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. eghbelham@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPreeclampsia is a common hypertensive disorder of pregnancy, which is associated with reduced placental perfusion and adverse fetal outcomes. Despite its clinical importance, fetal renal hemodynamics in pregnancies with preeclampsia has received little attention. Doppler ultrasound is a noninvasive method for assessing vascular resistance and perfusion in the fetal circulation, including the renal arteries.

methodsIn this cross-sectional case-control study, 160 pregnant women between 25 and 40 weeks of gestation were included in the study. Participants were divided into two groups: preeclampsia (n = 73) and control (n = 87), each containing 30 fetuses diagnosed with IUGR (Total 60 fetuses). Fetal biometry and Doppler indices including pulsatility index, resistance index, systolic-diastolic ratio, end-diastolic flow, and peak systolic velocity were measured in the umbilical and renal arteries.

resultsThe preeclamptic group showed higher values ​​of umbilical artery PI and RI and lower values ​​of umbilical artery EDV and PSV. Also, the renal artery S/D ratio was higher in this group. In mothers with preeclampsia, IUGR fetuses had higher values ​​of umbilical artery PI and RI and lower values ​​of umbilical artery EDV compared to normally growing fetuses. Renal artery PSV was lower in IUGR fetuses than in non-IUGR fetuses. Severe preeclampsia was associated with higher umbilical artery EDV values, indicating reduced vascular resistance in the fetal umbilical arteries.

conclusionThis study shows that abnormal fetal renal artery Doppler indices are more common in pregnancies with preeclampsia and IUGR, indicating increased vascular resistance and reduced renal perfusion. The use of renal artery Doppler can improve prenatal monitoring and risk stratification in high-risk pregnancies.

Indexed as

Fetal Growth RetardationFetusPre-EclampsiaRenal ArteryUltrasonography, PrenatalAdultBlood Flow VelocityCase-Control StudiesCross-Sectional StudiesFemaleHumansPregnancyUltrasonography, DopplerUmbilical ArteriesVascular ResistanceDoppler ultrasoundFetal renal arteryIntrauterine growth restrictionPreeclampsiaResistance index

Identifiers

PMID41673618
PMCPMC12998054

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