Evidence map›Paper›PMID 41673370›Full record

ArticleJournal of assisted reproduction and genetics2026

Factors influencing decisions regarding the fate of frozen embryos in reproductive treatments.

Beatriz Castilho, Cristina Nogueira-Silva, Pedro Brandão

Abstract read
In one paragraph

Article in Journal of assisted reproduction and genetics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Beatriz CastilhoSchool of Medicine, University of Minho, Braga, Portugal.
Cristina Nogueira-SilvaSchool of Medicine, University of Minho, Braga, Portugal.
Pedro BrandãoNext Fertility Portugal, Faro, Portugal. pedro.brandao@nextfertility.pt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAdvances in assisted reproductive technologies (ART) have led to an increasing number of surplus embryos being cryopreserved. Deciding the fate of these embryos poses complex emotional, ethical, and practical challenges. Understanding the factors that influence these decisions is critical in improving patient counseling and ART policy. This study aimed to analyze patterns in embryo disposition decisions across 6 years in a Portuguese ART center, focusing on differences by family type, patient age, and temporal trends.

methodsWe conducted a retrospective quantitative analysis of embryo disposition forms completed between 2017 and 2022, covering 3494 patients. Data were categorized by year, relationship group (different-sex couples, female couples, and single women), and final decision.

resultsDisposition decisions vary significantly by relationship group. Female couples were more likely to donate embryos to others (31.8%, p = 0.007) and less likely to discard them (15.9%, p = 0.03) than different-sex couples, who had the highest discard rate (26.5%). Single women showed intermediate behaviors. Age was a significant factor: those who donated embryos, particularly to others, were older (mean = 40.6 years) than those who kept or discarded them. No significant differences were found in relation to the number of embryos stored. Temporal analysis showed variation across years, with a notable increase in donations to research in recent years.

conclusionsFamily type and age are important factors influencing embryo disposition decisions, while the number of embryos appears to have a limited impact.

Indexed as

CryopreservationDecision MakingEmbryo DispositionReproductive Techniques, AssistedAdultEmbryo TransferFemaleFertilization in VitroHumansMalePregnancyRetrospective StudiesAssisted reproductionCryopreservationEmbryo dispositionEthics in ART

Identifiers

PMID41673370
PMCPMC13103224

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.