Evidence map›Paper›PMID 41673359›Full record

ArticleOrthopadie (Heidelberg, Germany)2026

[Musculoskeletal pathology in children with infantile cerebral palsy: a new classification system].

L M Kessling, R A van Stralen, J J Tolk, H K Graham, E Rutz

Abstract readEnglish Abstract
In one paragraph

Article in Orthopadie (Heidelberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

L M KesslingAbteilung für Orthopädie und Sportmedizin, Erasmus MC - Sophia Kinderkrankenhaus, Erasmus Medical Center, 3015 GD, Rotterdam, Niederlande.
R A van StralenAbteilung für Orthopädie und Sportmedizin, Erasmus MC - Sophia Kinderkrankenhaus, Erasmus Medical Center, 3015 GD, Rotterdam, Niederlande. r.vanstralen-bosboom@erasmusmc.nl.
J J TolkAbteilung für Orthopädie und Sportmedizin, Erasmus MC - Sophia Kinderkrankenhaus, Erasmus Medical Center, 3015 GD, Rotterdam, Niederlande.
H K GrahamMurdoch Children's Research Institute (MCRI), Victoria 3052, Parkville, Australien.
E RutzMurdoch Children's Research Institute (MCRI), Victoria 3052, Parkville, Australien.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCerebral palsy (CP) is one of the most common causes of physical disability in childhood. While the Gross Motor Function Classification System (GMFCS) describes motor abilities, a unified classification for musculoskeletal pathologies was lacking. The newly proposed four-stage system-based on the Mercer Rang model-describes the progression of lower limb pathology and supports diagnosis, treatment planning, and research. STAGE 1: Hypertonia: From birth to about 6 years, spasticity and delayed motor development predominate; contractures are rare. Early intervention and spasticity management (e.g., botulinum toxin) are the focus. STAGE 2: Contractures: Between the ages of 4 and 12 years, discrepancies between muscle-tendon length and bone growth cause a reduced range of motion. Surgical muscle or tendon lengthening may be indicated. STAGE 3: Bony deformities: Bony deformities such as increased femoral anteversion or pes valgus occur simultaneously with soft tissue contractures; rotational osteotomies and combined multilevel surgeries (SEMLS) are often required. STAGE 4: Decompensated pathology: After puberty, irreversible deformities and joint degeneration develop. Surgery usually aims at pain reduction or stabilization (e.g., arthrodesis).

conclusionThis classification raises awareness of disease progression, helps select stage-appropriate treatments, and may prevent over- or undertreatment. Early recognition and intervention are crucial to avoid decompensation and improve long-term musculoskeletal and functional outcomes.

Indexed as

Cerebral PalsyMusculoskeletal DiseasesChildChild, PreschoolContractureFemaleHumansInfantMaleChildContractureLower extremityMusculoskeletal abnormalitiesTreatment outcome

Identifiers

PMID41673359
PMCPMC13427808

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.