Evidence map›Paper›PMID 41673348›Full record

ArticleJournal of fluorescence2026

Exploration of a Novel Thiadiazole Derivative: Design, Synthesis, Biological Evaluation (In Vitro and in Silico), and DFT Studies.

Yassine Riadi, R Rajesh, Bharath Kumar Chagaleti, Ali Altharawi, Deepthi Joseph, Mohammed H Geesi, Taibah Aldakhil, Obaid Afzal, Ali Oubella, Reda A Haggam

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Article in Journal of fluorescence, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yassine RiadiDepartment of Pharmaceutical Chemistry, College of Pharmacy, Prince Sattam bin Abdulaziz University, Al-Kharj, Saudi Arabia.
R RajeshDepartment of Physics, Vel Tech High Tech Dr.Rangarajan Dr.Sakunthala Engineering College, Avadi, Chennai, 600 062, Tamil Nadu, India.
Bharath Kumar ChagaletiDepartment of Pharmaceutical Chemistry, Faculty of Medicine and Health Sciences, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur, Chengalpattu, 603203, Tamil Nadu, India. chagalek@srmist.edu.in.
Ali AltharawiDepartment of Pharmaceutical Chemistry, College of Pharmacy, Prince Sattam bin Abdulaziz University, Al-Kharj, Saudi Arabia.
Deepthi JosephDepartment of Electrical and Electronics Engineering, Vel Tech Multi Tech Dr.Rangarajan Dr.Sakunthala Engineering College, Avadi, Chennai, India.
Mohammed H GeesiDepartment of Chemistry, College of Science and Humanities in Al-Kharj, Prince Sattam bin Abdulaziz University, Al-Kharj, Saudi Arabia.
Taibah AldakhilDepartment of Pharmaceutical Chemistry, College of Pharmacy, Prince Sattam bin Abdulaziz University, Al-Kharj, Saudi Arabia.
Obaid AfzalDepartment of Pharmaceutical Chemistry, College of Pharmacy, Prince Sattam bin Abdulaziz University, Al-Kharj, Saudi Arabia.
Ali OubellaLaboratory of Organic & Physical Chemistry, Applied Bioorganic Chemistry Team, Faculty of Sciences, Ibn Zohr University, Agadir, Morocco.
Reda A HaggamDepartment of Chemistry, Faculty of Science, Islamic University of Madinah, Madinah, 42351, Saudi Arabia. relhaggan@iu.edu.sa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we describe the stepwise synthesis and thorough structural elucidation of a newly designed thiadiazole-based hybrid molecule, referred to as compound 5. Its chemical framework was confirmed through an array of spectroscopic analyses, including

Indexed as

Antineoplastic AgentsDensity Functional TheoryDrug DesignThiadiazolesCell Line, TumorCell ProliferationDrug Screening Assays, AntitumorHumansMolecular Docking SimulationMolecular StructureStructure-Activity RelationshipAntineoplastic AgentsThiadiazolesCycloadditionCytotoxicityDFTIsoxazolesMolecular dynamics

Identifiers

PMID41673348

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.