Evidence map›Paper›PMID 41673305›Full record

ArticleEvidence-based dentistry2026

Reuse and recycle: is autogenous tooth graft effective for alveolar ridge preservation?

Sophie Mills

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Article in Evidence-based dentistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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1 author.

Sophie MillsOral and Maxillofacial Surgery Department, Norfolk and Norwich University Hospital, Norwich, UK. sophiemills20@outlook.com.ORCID http://orcid.org/0000-0001-7400-124X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

a commentary onMahardawi B, Jiaranuchart S, Phrueksotsai C, Panya S, Arunjaroensuk S, Pimkhaokham A. Using autogenous tooth graft for alveolar ridge preservation: A systematic review and meta-analysis. J Prosthet Dent. 2025 Apr 28:S0022-3913(25)00299-9.  https://doi.org/10.1016/j.prosdent.2025.04.002 .

designA systematic review with meta-analysis was conducted to determine if autogenous tooth graft (ATG) was effective at maintaining alveolar ridge dimensions and stimulating bone formation in patient's undergoing exodontia, compared with spontaneous healing or other bone grafting materials. PRISMA guidelines were adhered to, and PICOS were used to develop the search question. CASE SELECTION: Three databases and non-peer-reviewed literature were reviewed independently by two authors. Inclusion criteria were randomised controlled trials comparing ATG with spontaneous healing or other grafting materials in human models. Studies that mixed bone grafting materials were excluded. DATA ANALYSIS: A meta-analysis assessed clinical significance with a 95% confidence interval, using the standardised mean difference to analyse alveolar ridge changes, and mean difference to assess bone regeneration. The random-effect model was applied to all analyses, and the GRADE system was used to determine the level of effect on ridge dimensions.

resultsAfter screening, fourteen studies were included in the meta-analysis. ATG was found to significantly reduce horizontal ridge resorption compared with ungrafted sockets, but did not perform superiorly compared with other grafting materials. There was a higher percentage of new bone formation at ATG sites, and no evidence that ATG compromised implant placement.

conclusionsATG is a valid alternative to other grafting materials for alveolar ridge preservation and may offer a histological advantage of stimulating more bone formation. Further clinical studies with increased sample size, longer follow-up, and standardised protocols are required to confirm clinical outcomes.

Indexed as

Alveolar Bone LossAlveolar ProcessAlveolar Ridge AugmentationToothBone TransplantationHumansMeta-Analysis as TopicSystematic Reviews as Topic

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.