Evidence map›Paper›PMID 41673280›Full record

Observational studyAesthetic plastic surgery2026

ChatGPT-5 Matches Surgeon-Level Assessment of Facelift Candidacy: A Pilot Proof-of-Concept Study.

Ayman T Saeed, R William F Breakey, Daniel B Saleh, Kemal Tunç Tiryaki, Bryan J Mayou, Tariq M Saeed

Abstract readObservational StudyMulticenter Study
PubMed Publisher
In one paragraph

Observational study in Aesthetic plastic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ayman T SaeedPlastic Surgery Department, Dr Tariq Hospital, Manama, Bahrain. aymantsaeed@gmail.com.ORCID http://orcid.org/0000-0001-9630-1913
R William F BreakeyPlastic Surgery Department, Leeds General Infirmary, Leeds, UK.
Daniel B SalehPlastic Surgery Department, Royal Victoria Infirmary, Newcastle-upon-Tyne, UK.
Kemal Tunç TiryakiPlastic Surgery Department, Cadogan Clinic, London, UK.
Bryan J MayouPlastic Surgery Department, Cadogan Clinic, London, UK.
Tariq M SaeedPlastic Surgery Department, Dr Tariq Hospital, Manama, Bahrain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe use of multimodal artificial intelligence (AI) in plastic surgery is steadily increasing. Whether a general-purpose multimodal AI tool can, from photographs alone, assess facial aging and facelift candidacy at a level comparable to board-certified specialist plastic surgeons remains unknown.

objectivesTo determine if ChatGPT-5 (OpenAI, San Francisco, CA, USA) can identify facial aging features, stratify severity, and judge facelift candidacy from photographs alone, compared with board-certified plastic surgeons.

methodsTwo-center observational pilot. Twenty-two volunteers (mean age 42.0 ± 16.8 years; median 34 years; range 24-80) provided standardized four-view facial composite photographs. Five board-certified plastic surgeons independently completed an eight-item questionnaire per case. ChatGPT-5 assessed the same images with identical wording. Assessments were image-only and blinded (no demographics/history). Surgeon consensus was defined by plurality. Primary outcomes were agreement and Cohen's κ; for ordinal items, weighted κ, Spearman's ρ, and mean absolute error (MAE) were reported. McNemar's test assessed discordance for binary items.

resultsFor facelift candidacy, agreement was 95.5% (21/22; Cohen's κ = 0.91; McNemar P = 1.00). For binary aging features, agreement ranged from 81.8 to 90.9% (κ ≈ 0.61 to 0.81). For ordinal severity (lower face and midface), exact agreement was 77.3%, disagreements were adjacent only, weighted κ = 0.74 to 0.86, Spearman's ρ = 0.84 (P < .001). Inter-surgeon agreement on ordinal items was moderate to fair. For the adjunct-procedure recommendation, Top-1 accuracy was 70.6% (12/17; κ = 0.58) and Top-2 agreement was 77.3% (17/22).

conclusionsIn a blinded, standardized-photograph setting, ChatGPT-5 matched surgeons on binary facelift candidacy assessment and closely tracked severity grading with small, one-level differences at most. These findings may support use as a decision-support tool (triage, patient education) while surgeons retain hands-on examination and personalized planning. Larger, multicenter studies with more diverse image datasets are warranted to confirm generalizability and define deployment standards. LEVEL OF EVIDENCE IV: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Indexed as

RhytidoplastySkin AgingAdultAgedAged, 80 and overFemaleGenerative Artificial IntelligenceHumansMaleMiddle AgedPhotographyPilot ProjectsProof of Concept StudyYoung AdultArtificial intelligenceChatGPTFaceliftFacial aging

Identifiers

PMID41673280

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.