Evidence map›Paper›PMID 41673213›Full record

ArticleActa neurochirurgica2026

Perfusion changes associated with intratumoral embolization and feeder occlusion for meningiomas: an arterial spin labeling study.

Masao Fukumura, Hideki Kashiwagi, Kohei Yoshimura, Takuya Kosaka, Yusuke Fukuo, Satoshi Takai, Yuichirou Tsuji, Naoki Omura, Gen Futamura, Ryokichi Yagi and 7 more

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Article in Acta neurochirurgica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

17 authors.

Masao FukumuraDepartment of Neurosurgery and Neuroendovascular Therapy, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, 569-8686, Japan. masao.fukumura@ompu.ac.jp.ORCID http://orcid.org/0009-0008-0615-3223
Hideki KashiwagiDepartment of Neurosurgery and Neuroendovascular Therapy, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, 569-8686, Japan.
Kohei YoshimuraDepartment of Neurosurgery and Neuroendovascular Therapy, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, 569-8686, Japan.
Takuya KosakaDepartment of Neurosurgery and Neuroendovascular Therapy, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, 569-8686, Japan.
Yusuke FukuoDepartment of Neurosurgery and Neuroendovascular Therapy, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, 569-8686, Japan.
Satoshi TakaiDepartment of Neurosurgery and Neuroendovascular Therapy, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, 569-8686, Japan.
Yuichirou TsujiDepartment of Neurosurgery and Neuroendovascular Therapy, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, 569-8686, Japan.
Naoki OmuraDepartment of Neurosurgery and Neuroendovascular Therapy, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, 569-8686, Japan.
Gen FutamuraDepartment of Neurosurgery and Neuroendovascular Therapy, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, 569-8686, Japan.
Ryokichi YagiDepartment of Neurosurgery and Neuroendovascular Therapy, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, 569-8686, Japan.
Ryo HiramatsuDepartment of Neurosurgery and Neuroendovascular Therapy, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, 569-8686, Japan.
Masahiro KamedaDepartment of Neurosurgery and Neuroendovascular Therapy, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, 569-8686, Japan.
Naosuke NonoguchiDepartment of Neurosurgery and Neuroendovascular Therapy, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, 569-8686, Japan.
Motomasa FuruseDepartment of Neurosurgery and Neuroendovascular Therapy, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, 569-8686, Japan.
Shinji KawabataDepartment of Neurosurgery and Neuroendovascular Therapy, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, 569-8686, Japan.
Toshihiro TakamiDepartment of Neurosurgery and Neuroendovascular Therapy, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, 569-8686, Japan.
Masahiko WanibuchiDepartment of Neurosurgery and Neuroendovascular Therapy, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, 569-8686, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPreoperative embolization for meningiomas has been used as an adjuvant therapy for surgery, although its clinical benefits remain controversial. Among embolization strategies, intratumoral embolization has been suggested to reduce tumor blood flow (TBF) more effectively than feeder occlusion; however, objective perfusion-based evaluations remain limited. The purpose of this study was to explore perfusion changes associated with feeder occlusion and intratumoral embolization using arterial spin labeling (ASL).

methodsForty-three consecutive patients who underwent preoperative embolization for meningiomas and pre- and post-embolization ASL were classified into intratumoral embolization and feeder occlusion groups. The TBF and cerebral blood flow (CBF) of each patient were calculated from the ASL. The TBF/CBF (T/N) ratios and the flow reduction rate were evaluated for both intratumoral embolization and feeder occlusion groups.

resultsThe postoperative T/N ratio significantly decreased in the intratumoral embolization group compared with the preoperative T/N ratio (P = 0.003). Meanwhile, no significant change was observed in the feeder occlusion group (P = 0.36). The flow reduction rate was significantly higher in the intratumoral embolization group than in the feeder occlusion group (50.6% vs. 24.1%; P = 0.001).

conclusionsIn this retrospective cohort, intratumoral embolization was associated with a greater reduction in tumor blood flow than feeder occlusion as assessed by ASL.

Indexed as

Cerebrovascular CirculationEmbolization, TherapeuticMeningeal NeoplasmsMeningiomaAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesSpin LabelsTreatment OutcomeSpin LabelsArterial spin labelingFeeder occlusionIntratumoral embolizationMeningioma

Identifiers

PMID41673213
PMCPMC12901263

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.