Evidence map›Paper›PMID 41673179›Full record

ArticleJournal of neuro-oncology2026

Post-traumatic growth in patients and caregivers after a primary brain tumor diagnosis.

Ashlee R Loughan, Sarah Ellen Braun, Autumn Lanoye, Kelcie Willis, Max Hernand

Abstract read
In one paragraph

Article in Journal of neuro-oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ashlee R LoughanSchool of Medicine, Virginia Commonwealth University, Richmond, VA, USA. ashlee.loughan@vcuhealth.org.ORCID http://orcid.org/0000-0002-7847-5992
Sarah Ellen BraunSchool of Medicine, Virginia Commonwealth University, Richmond, VA, USA.
Autumn LanoyeSchool of Medicine, Virginia Commonwealth University, Richmond, VA, USA.
Kelcie WillisDana Farber Cancer Center, Boston, MA, USA.
Max HernandDepartment of Psychology, Virginia Commonwealth University, Richmond, VA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIndividuals with primary brain tumors and their caregivers experience substantial psychological distress, yet positive psychological outcomes, such as post-traumatic growth (PTG), remain understudied. This study aimed to assess the prevalence and profile of PTG among primary brain tumor patients and caregivers, examine associations with demographic, medical, and psychological variables, and inform future neuro-oncology interventions.

methodsIn this prospective cross-sectional study, 141 participants (96 patients, 45 caregivers) completed validated surveys assessing PTG, depression, anxiety, and death anxiety. Participants were recruited via online neuro-oncology support and advocacy groups. PTG was measured using the Post-Traumatic Growth Inventory (PTGI). PTG profiles were examined using descriptives and associations between PTG and patient/caregiver characteristics, tumor-related medical variables, and psychological distress were examined using t-tests, ANOVAs, and Pearson correlations.

results70% of patients and 48.8% of caregivers reported moderate-to-high PTG. Appreciation of Life was the most frequently endorsed subscale in both groups. Patients with high-grade tumors exhibited significantly higher PTG than those with low-grade tumors; caregivers of patients with left-hemisphere tumors trended toward higher PTG. PTG was positively associated with death anxiety in patients but unrelated to depression or generalized anxiety in either group.

conclusionDespite significant distress, many patients and caregivers experience PTG following a brain tumor diagnosis, particularly in appreciating life. These findings highlight the potential for psychosocial and palliative interventions to harness PTG through meaning-making and existential engagement.

Indexed as

Brain NeoplasmsCaregiversPosttraumatic Growth, PsychologicalAdultAgedAnxietyCross-Sectional StudiesDepressionFemaleHumansMaleMiddle AgedProspective StudiesPsychological GrowthStress, PsychologicalSurveys and QuestionnairesCaregiversNeuro-oncologyPatientsPost traumatic growthWellbeing

Identifiers

PMID41673179
PMCPMC12894187

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.