ArticleNature2026
Targeting excessive cholesterol deposition alleviates secondary lymphoedema.
Abstract read
In one paragraph
Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Neuroimmune Regulation in Posttraumatic Bone Repair: From Inflammatory Transition to Neurovascular Coupling and Functional Recovery.Journal of cellular physiology · 2026Review
- Pan-Peroxisome Proliferator-Activated Receptor Agonist IVA337 Alleviates Secondary Lymphedema via Inhibiting TGFβ/SMAD2/3 Signaling Pathway.bioRxiv : the preprint server for biology · 2026Article
- Neuroimmune regulation of post-traumatic bone regeneration: focus on inflammatory switching and functional recovery.Frontiers in immunology · 2026Review
- Therapeutic targeting of local metabolic dysfunction in secondary lymphedema: mechanisms and opportunities.Frontiers in physiology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors.
Hwee Ying Lim *Immunology Translational Research Programme, Yong Loo Lin School of Medicine Department of Microbiology and Immunology, National University of Singapore, Singapore, Singapore.ORCID 0000-0003-3991-7855
Yuning Zhang *Immunology Translational Research Programme, Yong Loo Lin School of Medicine Department of Microbiology and Immunology, National University of Singapore, Singapore, Singapore.
Syaza Hazwany Mohammad AzharImmunology Translational Research Programme, Yong Loo Lin School of Medicine Department of Microbiology and Immunology, National University of Singapore, Singapore, Singapore.
Chung Hwee ThiamImmunology Translational Research Programme, Yong Loo Lin School of Medicine Department of Microbiology and Immunology, National University of Singapore, Singapore, Singapore.
Michaela TaylorImmunology Translational Research Programme, Yong Loo Lin School of Medicine Department of Microbiology and Immunology, National University of Singapore, Singapore, Singapore.
Xuan Han KohImmunology Translational Research Programme, Yong Loo Lin School of Medicine Department of Microbiology and Immunology, National University of Singapore, Singapore, Singapore.
Mohamed Ameen Shah Bin Mohamed YunosImmunology Translational Research Programme, Yong Loo Lin School of Medicine Department of Microbiology and Immunology, National University of Singapore, Singapore, Singapore.
Shu Wen TanImmunology Translational Research Programme, Yong Loo Lin School of Medicine Department of Microbiology and Immunology, National University of Singapore, Singapore, Singapore.
Sheau Yng LimImmunology Translational Research Programme, Yong Loo Lin School of Medicine Department of Microbiology and Immunology, National University of Singapore, Singapore, Singapore.ORCID 0000-0001-7487-0373
Wei Siong OngImmunology Translational Research Programme, Yong Loo Lin School of Medicine Department of Microbiology and Immunology, National University of Singapore, Singapore, Singapore.ORCID 0009-0002-2531-691X
Jasmine GohImmunology Translational Research Programme, Yong Loo Lin School of Medicine Department of Microbiology and Immunology, National University of Singapore, Singapore, Singapore.
Si Hui NgImmunology Translational Research Programme, Yong Loo Lin School of Medicine Department of Microbiology and Immunology, National University of Singapore, Singapore, Singapore.
Blake J CochranSchool of Biomedical Sciences, Faculty of Medicine and Health, University of New South Wales, Sydney, New South Wales, Australia.ORCID 0000-0002-9615-7939
Wai Kin ThamPrecision Medicine Translational Research Programme and Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Owen AngImmunology Translational Research Programme, Yong Loo Lin School of Medicine Department of Microbiology and Immunology, National University of Singapore, Singapore, Singapore.ORCID 0000-0002-7210-1586
Sheng Jie LimImmunology Translational Research Programme, Yong Loo Lin School of Medicine Department of Microbiology and Immunology, National University of Singapore, Singapore, Singapore.
Tze Chin LimImmunology Translational Research Programme, Yong Loo Lin School of Medicine Department of Microbiology and Immunology, National University of Singapore, Singapore, Singapore.
Yanjun ChenImmunology Translational Research Programme, Yong Loo Lin School of Medicine Department of Microbiology and Immunology, National University of Singapore, Singapore, Singapore.
Sebastian Frederik MauseDepartment of Internal Medicine I, Cardiology, University Hospital Aachen, RWTH Aachen University, Aachen, Germany.
Federico TortaPrecision Medicine Translational Research Programme and Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Markus R WenkPrecision Medicine Translational Research Programme and Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.ORCID 0000-0001-5447-7881
Kerry-Anne RyeSchool of Biomedical Sciences, Faculty of Medicine and Health, University of New South Wales, Sydney, New South Wales, Australia.ORCID 0000-0002-9751-917X
Bien Keem TanDepartment of Plastic, Reconstructive and Aesthetic Surgery, Singapore General hospital, Singapore, Singapore.
Veronique AngeliImmunology Translational Research Programme, Yong Loo Lin School of Medicine Department of Microbiology and Immunology, National University of Singapore, Singapore, Singapore. veronique.angeli@univ-cotedazur.fr.ORCID 0000-0002-2759-3497
Funding
French governmentH.Y.L.National Research AgencyNMRC
Abstract
Lymphoedema is a chronic debilitating disease caused by impaired lymphatic drainage and is characterized by tissue swelling, fat expansion, inflammation and fibrosis
Indexed as
CholesterolLymphedemaAdipocytesAdipose TissueAnimalsDisease Models, AnimalFemaleFibrosisHumansLymphatic VesselsMaleMiceMice, Inbred C57BLCholesterol
Identifiers
PMID
41673147What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.