Evidence map›Paper›PMID 41673001›Full record

ReviewNPJ biofilms and microbiomes2026

Microbial regulation of stress-associated signaling molecules and its role in health and disease.

Claire Sie, Carolina Tropini

Abstract readReview
In one paragraph

Review in NPJ biofilms and microbiomes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Decoding the power of the microbiome in human health.Frontiers in cellular and infection microbiology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Claire SieDepartment of Microbiology & Immunology, University of British Columbia, Vancouver, Canada.
Carolina TropiniDepartment of Microbiology & Immunology, University of British Columbia, Vancouver, Canada. carolina.tropini@ubc.ca.

Funding

Canada Tier 2 Research Chair CRC-2022-00036Canadian Institute for Advanced Research FL-001253 Appt 3362Four Year Fellowship - University of British Columbia 4YF-SieMichael Smith Health Research BC 18239
6 · The paper itself

Abstract

It has become increasingly appreciated that gut microbes influence host stress hormone responses through direct and indirect mechanisms. These relationships may have broad implications on hormone bioavailability, receptor signaling, and stress resilience. In this review, we summarize current evidence for microbe-stress factor interactions and their consequences for host physiology. We further examine how microbiota-stress crosstalk may contribute to inflammatory bowel disease, highlighting emerging mechanisms and potential microbiota-targeted therapies.

Indexed as

Gastrointestinal MicrobiomeInflammatory Bowel DiseasesSignal TransductionStress, PhysiologicalAnimalsHumans

Identifiers

PMID41673001
PMCPMC13005035

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.