Evidence map›Paper›PMID 41672713›Full record

ArticleAJNR. American journal of neuroradiology2026

Plaque-RADS and Neovascularization for Risk Stratification of Carotid Stenosis: A Bimodal Imaging Study.

Huan Zhu, Qihang Zhang, Tong Liu, Tong Chen, Chenyu Zhu, Tongyu Yang, Wenjie Li, Peijiong Wang, Tao Yu, Xingju Liu and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AJNR. American journal of neuroradiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Huan ZhuFrom the Beijing Neurosurgical Institute (H.Z., Qihang Z., T.L., C.Z., T. Yang., T. Yu., X.L., Qian Z., J.Z., Y.Z.), Capital Medical University, Beijing, China.
Qihang ZhangFrom the Beijing Neurosurgical Institute (H.Z., Qihang Z., T.L., C.Z., T. Yang., T. Yu., X.L., Qian Z., J.Z., Y.Z.), Capital Medical University, Beijing, China.
Tong LiuFrom the Beijing Neurosurgical Institute (H.Z., Qihang Z., T.L., C.Z., T. Yang., T. Yu., X.L., Qian Z., J.Z., Y.Z.), Capital Medical University, Beijing, China.
Tong ChenDepartment of Radiology (T.C.), Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Chenyu ZhuFrom the Beijing Neurosurgical Institute (H.Z., Qihang Z., T.L., C.Z., T. Yang., T. Yu., X.L., Qian Z., J.Z., Y.Z.), Capital Medical University, Beijing, China.
Tongyu YangFrom the Beijing Neurosurgical Institute (H.Z., Qihang Z., T.L., C.Z., T. Yang., T. Yu., X.L., Qian Z., J.Z., Y.Z.), Capital Medical University, Beijing, China.
Wenjie LiDepartment of Neurosurgery (W.L.), Peking University Third Hospital, Beijing, China.
Peijiong WangDepartment of Neurosurgery (P.W.), The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Tao YuFrom the Beijing Neurosurgical Institute (H.Z., Qihang Z., T.L., C.Z., T. Yang., T. Yu., X.L., Qian Z., J.Z., Y.Z.), Capital Medical University, Beijing, China.
Xingju LiuFrom the Beijing Neurosurgical Institute (H.Z., Qihang Z., T.L., C.Z., T. Yang., T. Yu., X.L., Qian Z., J.Z., Y.Z.), Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0003-2009-908X
Qian ZhangFrom the Beijing Neurosurgical Institute (H.Z., Qihang Z., T.L., C.Z., T. Yang., T. Yu., X.L., Qian Z., J.Z., Y.Z.), Capital Medical University, Beijing, China.
Jizong ZhaoFrom the Beijing Neurosurgical Institute (H.Z., Qihang Z., T.L., C.Z., T. Yang., T. Yu., X.L., Qian Z., J.Z., Y.Z.), Capital Medical University, Beijing, China.
Yan ZhangFrom the Beijing Neurosurgical Institute (H.Z., Qihang Z., T.L., C.Z., T. Yang., T. Yu., X.L., Qian Z., J.Z., Y.Z.), Capital Medical University, Beijing, China yanzhang166@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeThe Carotid Plaque Reporting and Data System (Plaque-RADS) score is a comprehensive imaging-based framework for assessing carotid plaque vulnerability. Intraplaque neovascularization (IPN) is closely linked to atherosclerotic plaque progression. However, the interrelationship between Plaque-RADS and IPN and their respective roles in patients with symptomatic carotid stenosis remains incompletely understood. MATERIALS AND

methodsWe retrospectively enrolled 128 patients with unilateral carotid artery stenosis who underwent carotid MR vessel wall imaging and contrast-enhanced ultrasound for integrated plaque characterization. Logistic regression was used to construct predictive models. Model performance was evaluated via the area under the receiver operating characteristic curve (AUC) with DeLong test for comparisons; the Net Reclassification Improvement (NRI) and Integrated Discrimination Improvement (IDI) were calculated to assess incremental predictive value.

resultsPatients with symptomatic stenosis had significantly higher Plaque-RADS scores (

conclusionsPlaque-RADS and the IPN grade are independent and complementary imaging biomarkers for identifying recent cerebrovascular events.

Indexed as

Carotid StenosisMagnetic Resonance AngiographyMultimodal ImagingNeovascularization, PathologicPlaque, AtheroscleroticUltrasonography, Carotid ArteriesAgedFemaleHumansMaleMiddle AgedRetrospective StudiesRisk AssessmentSensitivity and Specificity

Identifiers

PMID41672713
PMCPMC13431180

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.