Evidence map›Paper›PMID 41672578›Full record

ArticleBMJ open diabetes research & care2026

Feasibility and cost-effectiveness of at-home self-sampling screening for type 2 diabetes: a pilot screening study in Denmark.

Nuri Cayuelas Mateu, Peter Rossing, Kirsten Piepgras Neergaard, Tanja Thybo

Abstract read
In one paragraph

Article in BMJ open diabetes research & care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nuri Cayuelas MateuDiabetesforeningen, Glostrup, Denmark ncm@diabetes.dk.ORCID http://orcid.org/0000-0001-9125-947X
Peter RossingSteno Diabetes Center, Gentofte, Denmark.ORCID http://orcid.org/0000-0002-1531-4294
Kirsten Piepgras NeergaardSteno Diabetes Center, Gentofte, Denmark.
Tanja ThyboDiabetesforeningen, Glostrup, Denmark.ORCID http://orcid.org/0009-0007-5448-1208

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe increased use of HbA1c as a diagnostic criterion, novel methods to collect and store blood samples as well as the quality of national registers enable screening targeted individuals, who are not screened opportunistically. The study evaluates whether screening for type 2 diabetes using at-home self-sampling HbA1c tests, targeted people who have not had their HbA1c measured the last 2 years, is feasible and cost-effective. RESEARCH DESIGN AND

methodsDuring a period of 9 months, the Danish Diabetes Association mailed free capillary at-home self-sampling HbA1c tests to 8,000 randomly selected individuals aged 50-75 years who had not had their HbA1c measured in the past 2 years. The screening costs per screen-detected derived from the pilot study and estimated cost savings across HbA1c levels derived from a Danish simulation study was used to estimate cost-effectiveness.

resultsAbout 38% returned a blood sample. The share of participants with HbA1c of 48 mmol/mol (6.5%) and above was 1.7% (50/2913). The screening costs were 1.207 per screen-detected with type 2 diabetes. A national screening program targeting individuals aged 50 to 75 years, who have not had their HbA1c measured within the previous 2 years, is estimated to reduce healthcare costs and productivity losses by €1514 per screen-detected, if diagnosis is moved forward by 3 years, as derived from a Danish simulation study. Hence, the total social return ratio of the screening program is estimated to €1514/ €1183=1.28.

conclusionsThe study suggests that screening for type 2 diabetes using at-home self-sampling HbA1c tests, targeting individuals aged 50-75, who have not had their HbA1c measured the past 2 years, is feasible and cost-effective in Denmark.

Indexed as

BiomarkersCost-Benefit AnalysisDiabetes Mellitus, Type 2Glycated HemoglobinMass ScreeningSelf CareAgedCost-Effectiveness AnalysisDenmarkFeasibility StudiesFemaleFollow-Up StudiesHumansMaleMiddle AgedPilot ProjectsBiomarkersGlycated Hemoglobinhemoglobin A1c protein, humanCosts and Cost AnalysisDiabetes Mellitus, Type 2Early Diagnosis

Identifiers

PMID41672578
PMCPMC12911741

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.