Evidence map›Paper›PMID 41671517›Full record

ArticleJournal of natural products2026

Anti-Inflammatory Lindolin Alkaloids Repress the Transcription of the Microsomal Prostaglandin E

Paul M Jordan, Johannes Rassbach, Melina Gräfe, Lukas K Peltner, Karsten Willing, Lukas Zenkel, Kerstin Günther, Robin Sonnabend, Lars Regestein, Oliver Werz and 1 more

Abstract read
In one paragraph

Article in Journal of natural products, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Paul M JordanPharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University Jena, Philosophenweg 14, 07743 Jena, Germany.
Johannes RassbachPharmaceutical Microbiology, Institute of Pharmacy, Friedrich Schiller University Jena, Winzerlaer Strasse 2, 07745 Jena, Germany.
Melina GräfePharmaceutical Microbiology, Institute of Pharmacy, Friedrich Schiller University Jena, Winzerlaer Strasse 2, 07745 Jena, Germany.
Lukas K PeltnerPharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University Jena, Philosophenweg 14, 07743 Jena, Germany.
Karsten WillingBio Pilot Plant, Leibniz Institute for Natural Product Research and Infection, Biology, Hans Knöll Institute, Beutenbergstrasse 11a, 07745 Jena, Germany.
Lukas ZenkelPharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University Jena, Philosophenweg 14, 07743 Jena, Germany.
Kerstin GüntherPharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University Jena, Philosophenweg 14, 07743 Jena, Germany.ORCID 0000-0001-8230-5972
Robin SonnabendPharmaceutical Microbiology, Institute of Pharmacy, Friedrich Schiller University Jena, Winzerlaer Strasse 2, 07745 Jena, Germany.
Lars RegesteinBio Pilot Plant, Leibniz Institute for Natural Product Research and Infection, Biology, Hans Knöll Institute, Beutenbergstrasse 11a, 07745 Jena, Germany.ORCID 0000-0003-1258-7171
Oliver WerzPharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University Jena, Philosophenweg 14, 07743 Jena, Germany.ORCID 0000-0002-5064-4379
Markus GresslerPharmaceutical Microbiology, Institute of Pharmacy, Friedrich Schiller University Jena, Winzerlaer Strasse 2, 07745 Jena, Germany.ORCID 0000-0001-5669-7618

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The known indole-3-acetyl anthranilate lindolin A from the early-diverging fungus

Indexed as

AlkaloidsAnti-Inflammatory AgentsMacrophagesProstaglandin-E SynthasesDinoprostoneHumansMicrosomesMolecular Structureortho-AminobenzoatesStructure-Activity RelationshipAlkaloidsAnti-Inflammatory AgentsDinoprostoneortho-AminobenzoatesProstaglandin-E Synthases

Identifiers

PMID41671517
PMCPMC12954838

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.