Evidence map›Paper›PMID 41671365›Full record

ArticleScience advances2026

VapC36-mediated intrinsic stress adaption is required for copper tolerance and pathogenesis of

Arun Sharma, Gopinath Chattopadhyay, Manisha Singh, Munmun Bhasin, Prabhakar Babele, Raghavan Varadarajan, Ramandeep Singh

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Arun SharmaBRIC-Translational Health Science and Technology Institute, Faridabad-Gurugram expressway, Faridabad, Haryana, India.ORCID 0000-0002-4491-8732
Gopinath ChattopadhyayMolecular Biophysics Unit, Indian Institute of Science, Bangalore, Karnataka, India.ORCID 0000-0002-6408-1968
Manisha SinghBRIC-Translational Health Science and Technology Institute, Faridabad-Gurugram expressway, Faridabad, Haryana, India.
Munmun BhasinMolecular Biophysics Unit, Indian Institute of Science, Bangalore, Karnataka, India.ORCID 0000-0002-6867-3039
Prabhakar BabeleBRIC-Translational Health Science and Technology Institute, Faridabad-Gurugram expressway, Faridabad, Haryana, India.
Raghavan VaradarajanMolecular Biophysics Unit, Indian Institute of Science, Bangalore, Karnataka, India.ORCID 0000-0002-0823-7577
Ramandeep SinghBRIC-Translational Health Science and Technology Institute, Faridabad-Gurugram expressway, Faridabad, Haryana, India.ORCID 0000-0003-2705-3826

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here, we have used a comprehensive, system-wide approach to delineate the function of the virulence-associated proteins B and C 36 (VapBC36) toxin-antitoxin (TA) system in

Indexed as

Bacterial ProteinsCopperMycobacterium tuberculosisStress, PhysiologicalTuberculosisAnimalsGuinea PigsMiceProtein BindingToxin-Antitoxin SystemsVirulenceBacterial ProteinsCopper

Identifiers

PMID41671365
PMCPMC12893294

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.