Evidence map›Paper›PMID 41671011›Full record

ArticleRevista colombiana de obstetricia y ginecologia2025

Disseminated histoplasmosis in an HIV-positive patient mimicking advanced endometrial carcinoma. Case report

María Isabel Limia Pérez, José C Quílez Conde, Eva Beiro Felipe, Tamara Dehesa Martínez, Federico Morán Cuesta, María López Matarranz, Jesús Hilario De La Rosa Fernández, Carlos David Pérez Verdugo

Abstract readCase ReportsEnglish Abstract
In one paragraph

Article in Revista colombiana de obstetricia y ginecologia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

María Isabel Limia PérezServicio de Ginecología y Obstetricia, Hospital Universitario Basurto. Bilbao (España).ORCID 0009-0002-4734-7776
José C Quílez CondeServicio de Ginecología y Obstetricia, Hospital Universitario Basurto. Bilbao (España).
Eva Beiro FelipeDepartamento de Oncología Ginecológica, Servicio de Ginecología y Obstetricia, Hospital Universitario Basurto. Bilbao (España).
Tamara Dehesa MartínezDepartamento de Oncología Ginecológica, Servicio de Ginecología y Obstetricia, Hospital Universitario Basurto. Bilbao (España).
Federico Morán CuestaServicio de Medicina Interna, Hospital Universitario Basurto. Bilbao (España).
María López MatarranzServicio de Ginecología y Obstetricia, Hospital Universitario Basurto. Bilbao (España).
Jesús Hilario De La Rosa FernándezDepartamento de Oncología Ginecológica, Servicio de Ginecología y Obstetricia, Hospital Universitario Basurto. Bilbao (España).
Carlos David Pérez VerdugoDepartamento de Oncología Ginecológica, Servicio de Ginecología y Obstetricia, Hospital Universitario Basurto. Bilbao (España).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To present a case of disseminated histoplasmosis with endometrial involvement mimicking advanced endometrial carcinoma in a patient with HIV infection. The endometrial findings are described. Case presentation: A woman from Guinea-Bissau presented to a general hospital serving immigrant patients and those with public insurance, complaining of costal pain. Multiple pathological vertebral fractures were identified. During studies performed to clarify the cause of the fractures, a de novo diagnosis of HIV infection was made with a CD4 count of 395 cells/μL. Magnetic resonance imaging revealed images suggestive of vertebral abscesses and suspected endometrial cancer. Study of bone material showed presence of fungal spores and endometrial biopsy revealed non-necrotizing granulomas and histiocytic accumulations, without neoplastic lesion. Serological tests were positive for Histoplasma capsulatum. The patient was treated with liposomal amphotericin B and antiretroviral therapy with favorable clinical evolution on follow-up. Conclusions: It is important to consider opportunistic infections in the differential diagnosis of pelvic masses in immunocompromised patients. Additional studies are needed to determine the frequency of endometrial involvement in disseminated histoplasmosis and to establish specific diagnostic protocols.

Indexed as

AIDS-Related Opportunistic InfectionsEndometrial NeoplasmsHistoplasmosisHIV InfectionsAmphotericin BAntifungal AgentsDiagnosis, DifferentialFemaleHumansMagnetic Resonance ImagingAmphotericin BAntifungal Agentsliposomal amphotericin BEndometrial neoplasmsGynecologyHistoplasmosisHIVObstetrics

Identifiers

PMID41671011
PMCPMC12747723

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.