Evidence map›Paper›PMID 41670949›Full record

SynthesisRevista da Escola de Enfermagem da U S P2026

A meta-analysis of the literature evaluating the impact of vitamin D on female fertility and ovarian reserve function.

Shanfei Zhao, Wenling Zheng, Guanyun Long, Guanglin Liang

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Revista da Escola de Enfermagem da U S P, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shanfei ZhaoMaoming People 's Hospital, Center of Reproductive Medicine, Guangdong Province, China.ORCID 0000-0002-9431-9500
Wenling ZhengMaoming People 's Hospital, Center of Reproductive Medicine, Guangdong Province, China.ORCID 0009-0007-9105-5611
Guanyun LongMaoming People 's Hospital, Center of Reproductive Medicine, Guangdong Province, China.ORCID 0000-0003-2945-333X
Guanglin LiangMaoming People 's Hospital, Center of Reproductive Medicine, Guangdong Province, China.ORCID 0009-0005-0225-9408

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe current analysis study aims to estimate the role of vitamin D levels and supplementation on fertility reservation expressed as ovulation rate, pregnancy rate, and anti-Müllerian hormone (AMH).

methodA systematic literature review was conducted, and 2111 females were recruited to the current study. Inclusion criteria of the current study included comparative studies evaluating the role of vitamin D status and vitamin D supplementation on fertility parameters. Included studies published till December 2023. Continuous mode with random effect, were used for the analysis of data.

resultsTwenty-two studies, conducted on the impact of vitamin D on fertility parameters for females, were recruited in the current study. Vitamin D supplementation showed a significant enhancement in several parameters, including vitamin D level, number of dominant follicles, Ovulation rate, and pregnancy rate (MD = -2.3295% CI [-3.07, -1.56], MD = 0.81 95% CI [0.27, 1.35], MD = 0.81 95% CI [0.17, 1.45], and MD = 0.64 95% CI [0.20, 1.07], respectively). On the other hand, there was no significant impact on AMH levels.

conclusionFindings of current studies indicate a beneficial impact of vitamin D therapy on fertility outcomes regarding the number of dominant follicles, ovulation rate, and pregnancy rate.

Indexed as

FertilityOvarian ReserveVitamin DAnti-Mullerian HormoneDietary SupplementsFemaleHumansOvulationPregnancyPregnancy RateAnti-Mullerian HormoneVitamin D

Identifiers

PMID41670949
PMCPMC12893472

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.